Multicenter Network of Neonatal Intensive Care Units

该提案旨在证明埃默里大学儿科、新生儿围产期医学部和位于乔治亚州亚特兰大的埃默里地区围产期中心（ERPC）继续参与多中心新生儿合作研究网络的能力和承诺。儿科和该部门的概述都是提出的。该司负责在大学系统内的三家医院护理新生儿：格雷迪纪念医院，这是佐治亚州最大的医院，每年为大约4,500名新生儿提供护理；克劳福德·w·朗医院，一个拥有高风险产妇转运中心的设施，每年分娩约2400次；亚特兰大埃格莱斯顿儿童保健中心，这是一家三级转诊中心，每年有500多名新生儿直接接受新生儿服务，还有相当多的新生儿接受其他专科服务。这三所大学附属医院为具有无与伦比的病理多样性的广泛人群提供护理，从而为解决重要的研究问题提供了良好的环境。多年来，该部门与儿科的其他部门、埃默里大学医学院和罗林斯公共卫生学院的其他部门、乔治亚州人力资源部和亚特兰大的国家疾病控制和预防中心广泛合作，并参与了许多多中心随机临床试验。该提案详细描述了埃默里新生儿-围产期医学部门的学术生产力，并总结了首席研究员（PI）的研究活动。B. Stoll博士，PI，是国际公认的临床和流行病学研究者，其主要研究兴趣是新生儿感染，胎儿和新生儿的免疫发育，国际健康以及改善VLBW早产儿护理和结局的研究。综述了NICHD新生儿研究网络目前的活动。提出了一个供新网络考虑的概念建议。此外，该提案审查了临床和研究设施；产科和新生儿合作；医务人员和支助设施；可供临床研究的不同人群；母胎医学部；新生儿重症监护病房随访计划；围产期数据收集；研究护士人员配置和埃默里儿科的特殊研究优势，这些可能与网络研究有关。该司的工作人员由一群有凝聚力的新生儿学家组成，他们一直致力于临床研究，并支持该司继续参与新生儿网络。此外，通过她目前参与的新生儿网络和其他正在进行的和先前的国家和国际研究项目，PI已经证明了她与其他临床中心和科学团体合作的能力。

This proposal aims to demonstrate the ability and the commitment of the Emory University Department of Pediatrics, Division of Neonatal- Perinatal Medicine and the Emory Regional Perinatal Center (ERPC) in Atlanta, Georgia to continue their participation in the Cooperative Multicenter Neonatal Research Network. An overview of both the Department of Pediatrics and the Division is presented. The Division is responsible for the care of neonates at three hospitals within the University system: Grady Memorial Hospital, the largest hospital in the state of Georgia to provide indigent care with approximately 4,500 deliveries per year; Crawford W. Long Hospital, a facility with a high risk maternal transport center and approximately 2400 deliveries per year; and Children's Healthcare of Atlanta at Egleston, a tertiary referral center with over 500 neonates admitted directly to the neonatology service each year and a significant number admitted to other subspecialty services. These three university-affiliated hospitals provide care to a remarkably broad-based population with unparalleled pathological diversity, thus providing an excellent setting to address important research questions. Over the years, the Division has collaborated extensively with other Divisions within the Department of Pediatrics, other Departments at the Emory University School of Medicine and the Rollins School of Public Health, the Georgia Department of Human Resources, and the national Centers for Disease Control and Prevention in Atlanta and has participated in many multicenter randomized clinical trials. This proposal describes in detail the academic productivity of the Emory Division of Neonatal-Perinatal Medicine and summarizes the research activities of the Principal Investigator (PI). Dr. B. Stoll, the PI, is an internationally recognized clinical and epidemiologic investigator whose major research interests are neonatal infections, immune development of the fetus and newborn, international health, and studies to improve the care and outcome of VLBW preterm infants. Current activities of the NICHD Neonatal Research Network are reviewed. A concept proposal for consideration by the new Network is presented. In addition, the proposal reviews clinical and research facilities; obstetrical and neonatal cooperation; medical staff and support facilities; the varied population available for clinical research; the Maternal-Fetal Medicine Unit; the NICU follow-up program; perinatal data collection; research nurse staffing and special research strengths of the Emory Department of Pediatrics that may be relevant to Network research. The Division is staffed by a cohesive group of neonatologists who have an ongoing commitment to clinical research and support the Division's continued participation in the Neonatal Network. Moreover, the PI has demonstrated her ability to work collaboratively with other clinical centers and scientific groups through her current participation in the Neonatal Network and other ongoing and prior national and international research projects.