Multicenter Network of Neonatal Intensive Care Units

该提案旨在展示埃默里大学儿科、新生儿-围产期医学部和位于佐治亚州亚特兰大的埃默里地区围产期中心(ERPC)继续参与合作多中心新生儿研究网络的能力和承诺。介绍了儿科和该司的概况。该司负责在大学系统内的三家医院提供新生儿护理：格雷迪纪念医院是佐治亚州最大的提供贫困护理的医院，每年约有4 500人次接生；克劳福德·W·朗医院是一家具有高风险孕产妇转运中心的设施，每年约有2400人次接生；以及位于埃格尔斯顿的亚特兰大儿童医疗保健，这是一个三级转诊中心，每年有500多名新生儿直接进入新生儿服务中心，其中相当多的新生儿进入其他专科服务。这三所大学附属医院为具有无与伦比的病理多样性的基础非常广泛的人群提供护理，从而为解决重要的研究问题提供了一个极好的环境。多年来，该司与儿科部门、埃默里大学医学院和罗林斯公共卫生学院的其他部门、佐治亚州人力资源部和亚特兰大的国家疾病控制和预防中心广泛合作，并参与了许多多中心随机临床试验。该提案详细描述了埃默里新生儿-围产期医学部的学术生产力，并总结了首席研究员(PI)的研究活动。B·斯托尔博士是国际公认的临床和流行病学调查员，他的主要研究兴趣是新生儿感染、胎儿和新生儿的免疫发育、国际健康以及改善极低出生体重早产儿护理和结局的研究。回顾了NICHD新生儿研究网络目前的活动。提出了一项概念建议，供新网络审议。此外，该提案还审查了临床和研究设施；产科和新生儿的合作；医务人员和支持设施；可用于临床研究的不同人群；母婴医学股；NICU后续计划；围产期数据收集；研究护士配备以及可能与网络研究相关的埃默里儿科部门的特殊研究优势。该司的工作人员是一群具有凝聚力的新生儿专家，他们不断致力于临床研究，并支持该司继续参与新生儿网络。此外，通过她目前参与的新生儿网络和其他正在进行的和以前的国内和国际研究项目，PI已经展示了她与其他临床中心和科学小组合作的能力。

This proposal aims to demonstrate the ability and the commitment of the Emory University Department of Pediatrics, Division of Neonatal- Perinatal Medicine and the Emory Regional Perinatal Center (ERPC) in Atlanta, Georgia to continue their participation in the Cooperative Multicenter Neonatal Research Network. An overview of both the Department of Pediatrics and the Division is presented. The Division is responsible for the care of neonates at three hospitals within the University system: Grady Memorial Hospital, the largest hospital in the state of Georgia to provide indigent care with approximately 4,500 deliveries per year; Crawford W. Long Hospital, a facility with a high risk maternal transport center and approximately 2400 deliveries per year; and Children's Healthcare of Atlanta at Egleston, a tertiary referral center with over 500 neonates admitted directly to the neonatology service each year and a significant number admitted to other subspecialty services. These three university-affiliated hospitals provide care to a remarkably broad-based population with unparalleled pathological diversity, thus providing an excellent setting to address important research questions. Over the years, the Division has collaborated extensively with other Divisions within the Department of Pediatrics, other Departments at the Emory University School of Medicine and the Rollins School of Public Health, the Georgia Department of Human Resources, and the national Centers for Disease Control and Prevention in Atlanta and has participated in many multicenter randomized clinical trials. This proposal describes in detail the academic productivity of the Emory Division of Neonatal-Perinatal Medicine and summarizes the research activities of the Principal Investigator (PI). Dr. B. Stoll, the PI, is an internationally recognized clinical and epidemiologic investigator whose major research interests are neonatal infections, immune development of the fetus and newborn, international health, and studies to improve the care and outcome of VLBW preterm infants. Current activities of the NICHD Neonatal Research Network are reviewed. A concept proposal for consideration by the new Network is presented. In addition, the proposal reviews clinical and research facilities; obstetrical and neonatal cooperation; medical staff and support facilities; the varied population available for clinical research; the Maternal-Fetal Medicine Unit; the NICU follow-up program; perinatal data collection; research nurse staffing and special research strengths of the Emory Department of Pediatrics that may be relevant to Network research. The Division is staffed by a cohesive group of neonatologists who have an ongoing commitment to clinical research and support the Division's continued participation in the Neonatal Network. Moreover, the PI has demonstrated her ability to work collaboratively with other clinical centers and scientific groups through her current participation in the Neonatal Network and other ongoing and prior national and international research projects.