ZEBRAFISH INTERNATIONAL RESOURCE CENTER

斑马鱼国际资源中心

• 批准号: 7153954
• 负责人: Monte Westerfield
• 金额: $ 159.04万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7153954
• 关键词: Internet; animal care; animal colony; animal genetic material tag; animal population genetics; communicable disease transmission; computer system design /evaluation; cryopreservation; developmental genetics; epizootiology; genetic models; genetic registry /resource /referral center; genetic strain; genetically modified animals; handbook; information systems; mutant; sperm; veterinary medicine; veterinary science; zebrafish

DESCRIPTION (provided by applicant): Zebrafish has emerged as a premiere organism to study vertebrate development and genetics. Powerful techniques allow efficient generation and recovery of zebrafish mutations affecting genes that regulate developmental patterning, organogenesis, physiology, and behavior. Recent advances make it easy to study gene function in transgenic zebrafish and with antisense oligonucleotides. The functions of many of these genes are conserved among vertebrate groups. Thus, analysis of zebrafish mutations provides insights into gene function in other vertebrates, including humans. The Zebrafish Iinternational Resource Center has been established as a repository that provides animals, materials, and services to the research community. This proposal seeks continued funding to: 1) provide a centralized repository for zebrafish genetic stocks and research materials; 2) provide consultation and pathology services; and 3) develop improved zebrafish husbandry methods. These materials, services, and information will be made widely available to the research community.

描述（由申请人提供）：