ZEBRAFISH INTERNATIONAL RESOURCE CENTER
斑马鱼国际资源中心
基本信息
- 批准号:7392010
- 负责人:
- 金额:$ 152.21万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2006
- 资助国家:美国
- 起止时间:2006-07-01 至 2007-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): Zebrafish has emerged as a premiere organism to study vertebrate development and genetics. Powerful techniques allow efficient generation and recovery of zebrafish mutations affecting genes that regulate developmental patterning, organogenesis, physiology, and behavior. Recent advances make it easy to study gene function in transgenic zebrafish and with antisense oligonucleotides. The functions of many of these genes are conserved among vertebrate groups. Thus, analysis of zebrafish mutations provides insights into gene function in other vertebrates, including humans. The ZIRC has been established as a repository that provides animals, materials, and services to the research community. This proposal seeks continued funding to: 1) provide a centralized repository for zebrafish genetic stocks and research materials; 2) provide consultation and pathology services; and 3) develop improved zebrafish husbandry methods. These materials, services, and information will be made widely available to the research community.
这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金,因此可能会出现在其他CRISE条目中。列出的机构是针对中心的,而不一定是针对调查员的机构。描述(申请人提供):斑马鱼已成为研究脊椎动物发育和遗传学的首选生物。强大的技术可以有效地产生和恢复斑马鱼突变,影响调控发育模式、器官发生、生理和行为的基因。最近的进展使得研究转基因斑马鱼和反义寡核苷酸的基因功能变得容易。这些基因中的许多功能在脊椎动物群体中是保守的。因此,对斑马鱼突变的分析提供了对包括人类在内的其他脊椎动物基因功能的洞察。Zirc被建立为一个向研究界提供动物、材料和服务的储存库。这项提议寻求继续提供资金:1)提供斑马鱼遗传种群和研究材料的中央储存库;2)提供咨询和病理服务;以及3)发展改进的斑马鱼饲养方法。这些材料、服务和信息将广泛提供给研究界。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Monte Westerfield其他文献
Monte Westerfield的其他文献
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{{ truncateString('Monte Westerfield', 18)}}的其他基金
Genetic and functional analysis of YPEL3 and its link to disease
YPEL3 的遗传和功能分析及其与疾病的联系
- 批准号:
9070011 - 财政年份:2015
- 资助金额:
$ 152.21万 - 项目类别:
The functions of PDZ domain scaffold proteins in Usher syndrome
PDZ结构域支架蛋白在Usher综合征中的功能
- 批准号:
8099700 - 财政年份:2010
- 资助金额:
$ 152.21万 - 项目类别:
The functions of PDZ domain scaffold proteins in Usher syndrome
PDZ结构域支架蛋白在Usher综合征中的功能
- 批准号:
8471097 - 财政年份:2010
- 资助金额:
$ 152.21万 - 项目类别:
The functions of PDZ domain scaffold proteins in Usher syndrome
PDZ结构域支架蛋白在Usher综合征中的功能
- 批准号:
8662744 - 财政年份:2010
- 资助金额:
$ 152.21万 - 项目类别:
The functions of PDZ domain scaffold proteins in Usher syndrome
PDZ结构域支架蛋白在Usher综合征中的功能
- 批准号:
8301725 - 财政年份:2010
- 资助金额:
$ 152.21万 - 项目类别: