The Synthesis and Development of New Imaging Agents of the Translocator Protein

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The PhD project will develop new organic synthetic chemistry for the rapid and efficient preparation of chemical imaging agents that can be used to study a range of neurological diseases associated with the translocator protein. In particular, we will investigate new transition metal catalysed transformations in combination with one-pot multi-bond forming reaction processes for the preparation of highly functional, drug-like heterocyclic scaffolds. These processes will be used to prepare molecular tracers that can be used in PET and SPECT imaging