ABCA1 _ an Intersection between Infection, Atherosclerosis and Metabolic Disorders
ABCA1 _感染、动脉粥样硬化和代谢紊乱之间的交叉点
基本信息
- 批准号:nhmrc : 1019847
- 负责人:
- 金额:$ 43.6万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Project Grants
- 财政年份:2012
- 资助国家:澳大利亚
- 起止时间:2012-01-01 至 2014-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Pathogens interfere with cellular cholesterol metabolism in order to support their lifecycle. Such interference may cause diseases not usually associated with infection, like cardiovascular disease. Restoring normal cholesterol metabolism may help treating infection and its metabolic consequences. We will investigate molecular, cellular and physiological mechanisms of interaction of pathogens with cholesterol metabolism to find a key point that can be targeted for therapeutic intervention.
病原体干扰细胞胆固醇代谢,以支持其生命周期。这种干扰可能导致通常与感染无关的疾病,如心血管疾病。恢复正常的胆固醇代谢可能有助于治疗感染及其代谢后果。我们将研究病原体与胆固醇代谢相互作用的分子,细胞和生理机制,以找到一个可以靶向治疗干预的关键点。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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A/Pr Barry Slobedman其他文献
A/Pr Barry Slobedman的其他文献
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{{ truncateString('A/Pr Barry Slobedman', 18)}}的其他基金
Understanding the role of ongoing viral activity in herpes simplex virus latency
了解持续病毒活动在单纯疱疹病毒潜伏期中的作用
- 批准号:
nhmrc : GNT1126599 - 财政年份:2017
- 资助金额:
$ 43.6万 - 项目类别:
Project Grants
Mechanisms by which varicella zoster virus and herpes simplex virus control host functions to enhance pathogenesis
水痘带状疱疹病毒和单纯疱疹病毒控制宿主功能增强发病机制
- 批准号:
nhmrc : GNT1088005 - 财政年份:2015
- 资助金额:
$ 43.6万 - 项目类别:
Project Grants
How does human cytomegalovirus control host responses to infection to facilitate human disease?
人类巨细胞病毒如何控制宿主对感染的反应以促进人类疾病?
- 批准号:
nhmrc : GNT1063738 - 财政年份:2014
- 资助金额:
$ 43.6万 - 项目类别:
Project Grants
How does varicella zoster virus cause shingles and associated disease during infection of human ganglia?
水痘带状疱疹病毒在感染人类神经节期间如何引起带状疱疹和相关疾病?
- 批准号:
nhmrc : GNT1063744 - 财政年份:2014
- 资助金额:
$ 43.6万 - 项目类别:
Project Grants
Defining a virally-encoded molecular switch between productive and latent phases of human cytomegalovirus infection.
定义人类巨细胞病毒感染的生产期和潜伏期之间的病毒编码分子开关。
- 批准号:
nhmrc : 1030707 - 财政年份:2012
- 资助金额:
$ 43.6万 - 项目类别:
Project Grants
Human cytomegalovirus gene expression and functions during latent infection and reactivation
潜伏感染和再激活过程中人巨细胞病毒基因表达和功能
- 批准号:
nhmrc : 570962 - 财政年份:2009
- 资助金额:
$ 43.6万 - 项目类别:
NHMRC Project Grants
Pathogenesis of Persistent Human Virus Infections of Global Significance
具有全球意义的持续人类病毒感染的发病机制
- 批准号:
nhmrc : 358399 - 财政年份:2005
- 资助金额:
$ 43.6万 - 项目类别:
Programs
Viral and host cell gene expression during the establishment and maintenance phases of human cytomegalovirus latency
人巨细胞病毒潜伏期建立和维持阶段的病毒和宿主细胞基因表达
- 批准号:
nhmrc : 301943 - 财政年份:2004
- 资助金额:
$ 43.6万 - 项目类别:
NHMRC Project Grants
Interactions between HIV and mycobacterial infections of macrophages mediated by changes in gene expression
基因表达变化介导的艾滋病毒和巨噬细胞分枝杆菌感染之间的相互作用
- 批准号:
nhmrc : 307608 - 财政年份:2004
- 资助金额:
$ 43.6万 - 项目类别:
NHMRC Project Grants
Analysis of viral and cellular gene expression during human cytomegalovirus latent infection of hematopoietic cells
人巨细胞病毒潜伏感染造血细胞过程中病毒和细胞基因表达分析
- 批准号:
nhmrc : 153873 - 财政年份:2001
- 资助金额:
$ 43.6万 - 项目类别:
NHMRC Project Grants
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