SIGNAL TRANSDUCTION IN THE IMMUNE SYSTEM-FASEB CONF.

本申请为FASEB“免疫系统信号转导”夏季会议寻求部分资助，该会议将于2005年6月18日至23日在科罗拉多州斯诺马斯举行。会议的主要目标是全面关注免疫细胞在健康和疾病方面的反应所涉及的信号机制的最新进展。了解这些信号转导途径对于阐明感染、过敏、移植和恶性肿瘤反应的分子基础至关重要。免疫细胞信号传导在高校、科研院所和生物技术领域受到广泛关注。然而，在免疫学会议上，信号转导通常被作为一个附属主题进行讨论，很少有详细的报道。2000年，FASEB第一次关于“免疫系统信号转导”的会议提供了对免疫系统信号转导细节的深入关注。这次会议的成功使一些调查人员相信定期会议的价值。在此基础上，2003年夏天再次召开了会议，我们现在计划在2005年夏天召开一次会议。2005年会议将涵盖一系列主题，重点是将不同的信号机制整合到免疫生物学的各个组成部分中。将有三个主要目标：

This application seeks partial funding for a FASEB Summer Conference on "Signal Transduction in the Immune System", to be held June 18-23, 2005 in Snowmass, Colorado. The major goal of the conference will be to provide a comprehensive focus on recent advances regarding the signaling mechanisms involved in the responses of immune cells, both in health and in disease. An understanding of these signal transduction pathways is central to elucidating the molecular basis of the responses to infections, allergies, transplantation and malignancies. Widespread interest of immune cell signaling exists in universities, research institutes and biotechnology. However, signal transduction at immunology meetings is generally covered as an adjunct subject, with little detailed coverage. In 2000, the first FASEB meeting on "Signal Transduction in the Immune System" provided an in-depth focus on the details of signal transduction in the immune system. The success of that meeting convinced a number of investigators of the value of a regular meeting. On this basis, the meeting was repeated in the summer of 2003, and we arc now planning a meeting for the summer of 2005. The 2005 meeting will cover a spectrum of topics, with an emphasis on integrating the different signaling mechanisms into the various components of immune biology. There will be three main objectives: 1) To provide a critical and intensive overview of the current status of signaling proteins that control various immune functions. Our meeting will cover a full range of topics from an in-depth analysis of specific signaling molecules and networks, to the application of this knowledge to immunobiology. 2) To bring together senior scientists and young investigators in a convivial atmosphere of presentations and informal discussions. It is hoped that this environment will help develop the investigative skills and enthusiasm of students and young investigators by interacting with established investigators. 3) To continue a biannual forum for investigators interested in a comprehensive focus on signaling events in the immune system.