Training in Endocrinology, Diabetes, Clinical Nutrition

描述(由申请人提供)： 这项提案是为了继续支持俄勒冈健康与科学大学的内分泌学和新陈代谢研究培训计划。该计划的主要目标是通过在激励的大学环境中提供假设驱动的、基础的和以疾病为导向的研究方面的强化培训，为成功的科学职业生涯培养合格的受训人员，目前已进入第10个年头。应聘者将拥有医学博士、医学博士或博士学位。在大多数情况下(即医学博士和医学博士/博士候选人)，在研究培训之前，将进行一年的临床内分泌学和新陈代谢方面的集中培训，以及旨在教授内分泌学科学基础的正式活动。最初的临床培训年将通过机构资源提供资金。随后的两年将在一名知名研究人员的监督下，在假说驱动的内分泌研究方面提供第一手经验和培训，并将由这笔赠款资助。研究活动将由每周的期刊俱乐部、进行中的研究会议、内分泌大巡回和内分泌临床病例会议以及根据每个受训者的个人科学需求量身定做的正式研究生课程工作来补充。该项目的特殊优势包括：1)在生长因子、甲状腺、垂体、肾上腺、信号转导、分子遗传学、糖尿病、肥胖症、骨骼和矿物质代谢、血脂紊乱和生殖内分泌学等领域拥有广泛实力的教师的不同技能和兴趣。2)教师拥有雄厚的实验室资源，并设有综合临床研究中心，以促进最先进的临床研究培训。3)OHSU及其附属机构(Vollum研究所和俄勒冈国家灵长类动物研究中心)在临床、细胞和分子内分泌学及相关领域的出色研究环境。培训计划的一个主要前提是，在接下来的几十年里，对熟练的医生-调查人员的需求只会继续增加。该计划旨在培养独立的学术内分泌学家，他们将作为独立的实验室科学家发挥作用，能够开发未来解决内分泌疾病的研究计划。

DESCRIPTION (provided by applicant): This proposal is a request for continuing support of a research-based training program in Endocrinology and Metabolism at Oregon Health & Science University. The main goal of this program, now in its 10th year, is to prepare qualified trainees for successful scientific careers as independent investigators by providing intensive training in hypothesis-driven, basic and disease-oriented research in a stimulating ant collegial environment. Potential candidates will hold an MD, MD/PhD, or PhD degree. In most cases (i.e. MD and MD/PhD candidates), research training will be preceded by one year of concentrated training in clinical endocrinology and metabolism, and by formal activities designed to teach the scientific basis of endocrinology. The initial clinical year of training will be funded through institutional resources. The subsequent two years will be devoted to first hand experience and training in hypothesis-driven endocrine research under the supervision of an established investigator and will be funded by this grant. Research activities will be supplemented by weekly journal clubs, research-in-progress meetings, endocrine grand rounds, and endocrine clinical case conferences, and by formal graduate level course work tailored to the individual scientific needs of each trainee. The special strengths of this program include: 1) The diverse skills and interests of the faculty with broad strength in the areas of growth factors, thyroid, pituitary, adrenal, signal transduction, molecular genetics, diabetes, obesity, bone and mineral metabolism, lipid disorders, and reproductive endocrinology. 2) The substantial laboratory resources of the faculty and availability of a General Clinical Research Center, which facilitates training in state-of-the-art clinical investigation. 3) The outstanding environment for research in both clinical as well as cellular and molecular endocrinology and related areas at OHSU and its affiliated institutions (Vollum Institute and Oregon National Primate Research Center). A major premise of the training program is that the need for skilled physician-investigators will only continue to increase over the coming decades. This program seeks to train independent academic endocrinologists who will function as independent laboratory scientists capable of developing research programs that address endocrine disorders in the future.