Noninvasive Home Monitor for Sleep Apnea Testing

用于睡眠呼吸暂停测试的无创家用监视器

• 批准号: 6934909
• 负责人: BRIAN L CRAINE
• 金额: $ 10万
• 依托单位: WESTERN RESEARCH COMPANY, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-15 至 2005-10-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6934909
• 关键词: biomedical equipment development; clinical research; computer data analysis; computer system design /evaluation; electrocardiography; human subject; monitoring device; oximetry; polysomnography; portable biomedical equipment; respiratory disorder diagnosis; sleep apnea

DESCRIPTION (provided by applicant): Obstructive sleep apnea affects about 3-4% of the population including children. There is considerable associated morbidity and mortality. In particular there is a strong association with hypertension and cardiac disease. Daytime somnolence leads to increased traffic accidents and decreased worker production. The key diagnostic testing for this condition is overnight sleep testing or nocturnal polysomnography. Despite the seriousness of this medical condition about 80 percent of those afflicted are undiagnosed. This is due, in part, to the expense and lack of availability of standard polysomnography. This has lead to a great deal of interest in the development of portable testing systems that provide economical, readily available and accurate testing for obstructive sleep apnea at home. We propose a single type of sensor based monitoring system that would provide a reliable and simple to use unit that should allow for economical and efficient home testing. Although we propose the use of a single sensor to allow for a simple to use system, we incorporate data analysis methods that will allow for the recovery of three independent metrics for prediction of obstructive sleep apnea. This should allow for a more accurate testing system than current portable systems. Since the proposed system will correct the major problems with portable sleep testing instruments (practical, mechanical and provide multiple metrics for diagnostic accuracy), we anticipate that this project would result in a successful commercial product that would be beneficial to a large number of currently undiagnosed Americans.

描述（由申请人提供）：阻塞性睡眠呼吸暂停影响约 3-4% 的人口，包括儿童。有相当大的相关发病率和死亡率。特别是与高血压和心脏病有很强的关联。白天嗜睡会导致交通事故增加和工人生产力下降。这种情况的关键诊断测试是夜间睡眠测试或夜间多导睡眠图。尽管这种疾病很严重，但大约 80% 的患者并未得到诊断。这部分是由于标准多导睡眠图的费用高且缺乏可用性。这引起了人们对开发便携式测试系统的极大兴趣，该系统可以为家庭阻塞性睡眠呼吸暂停提供经济、方便且准确的测试。我们提出了一种基于单一类型传感器的监控系统，该系统将提供可靠且易于使用的装置，从而实现经济且高效的家庭测试。尽管我们建议使用单个传感器来实现简单易用的系统，但我们结合了数据分析方法，可以恢复三个独立的指标来预测阻塞性睡眠呼吸暂停。这应该允许比当前便携式系统更准确的测试系统。由于所提出的系统将纠正便携式睡眠测试仪器的主要问题（实用、机械并提供诊断准确性的多种指标），我们预计该项目将产生一个成功的商业产品，这将造福于大量目前未确诊的美国人。