INTERNATIONAL TRAINING PROGRAM IN EPIDEMIOLOGY OF AIDS

艾滋病流行病学国际培训计划

• 批准号: 7249674
• 负责人: QUARRAISHA ABDOOL KARIM
• 金额: $ 10.88万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7249674
• 关键词: AIDS; Africa; HIV infections; communicable disease control; education evaluation /planning; epidemiology; health care personnel education; health science manpower; health science research; human immunodeficiency virus 1; international cooperation; mentoring /mentor; postgraduate education; training; tuberculosis

DESCRIPTION (provided by applicant): The proposed training program builds on the successes and lessons of the previous 10 years as it takes a major leap forward. The growing research infrastructure, the growing local expertise, growing NIH funded research opportunities create a new set of challenges and opportunities for this hitherto successful AIDS/TB training program as the program adapts in response to meet the existing and emerging research training needs in South Africa and the region. The past 44 long-term and 69 short-term trainees of the program have been scientifically productive (515 publications including papers in Science, Nature, and Lancet), have made major new scientific contributions, have been instrumental to South Africa's success in securing NIH and other international grants and have taken up several key leadership positions. The continuum of training, research, and mentoring between the US and SA in the previous cycle has already gone some way towards equalizing the partnership between the US and South African but more still needs to be done, especially as the challenge of training for treatment provision and treatment program evaluations becomes more immediate. The emphasis of the program in this current cycle will be to identify critical gaps in existing centers of research excellence in South Africa and recruit, train and mentor appropriate enthusiastic, bright young and established mid-level investigators to provide them with the knowledge base and skills needed for the design and conduct of large-scale clinical trials (esp for vaccines and microbicides); pathogenesis studies, studies on the HIV/TB interaction and evaluation of the impact of ARV treatment. The goal is to strengthen existing and expand the number of independent HIV-related research teams in South Africa; strengthen South Africa's capacity to assume more of the country's and region's training needs and developing the skills needed to operationalize, implement and monitor the South African scale-up of AIDS treatment. Guided by the ongoing assessment of training priorities and with careful oversight from a balanced US-SA Scientific Advisory Committee, we will continue to provide as appropriate a variety of short-to-medium, and long-term training opportunities in the US and South Africa. Priority will be given to trainees from recognized AIDS research groups. Vigorous effort will go towards equalization of the training opportunities between the US and South Africa. This includes the establishment of a high quality masters program in epidemiology in South Africa taught initially jointly by US and South African faculty. A rich tapestry of AIDS and TB projects funded by NIH, CDC, and others offer diverse training and research opportunities to trainees for their placements. Overall, this program is designed to increase the number of independent established AIDS and TB researchers in South Africa so that there is local critical mass for future in-country mentorship and training. While this is a long-term goal, the proposed program sets about this task well armed with the most valuable lessons learnt in the last 5 years such as the importance of ongoing in-country mentorship, guidance and support, assistance with grant writing, and recruitment of candidates who are already in productive research groups.

描述（由申请人提供）：拟议的培训计划以前10年的成功和教训为基础，因为它取得了重大飞跃。 不断增长的研究基础设施，日益增长的本地专业知识，不断增长的NIH资助的研究机会为迄今为止成功的艾滋病/结核病培训计划带来了一系列新的挑战和机遇，随着该计划的适应性，以满足南非和该地区现有和新兴的研究培训需求。该计划的过去44名长期和69名短期学员在科学上是有效的（包括科学，自然和柳叶刀的论文在内的515名出版物），做出了重大的新科学贡献，对南非在确保NIH和其他国际赠款方面的成功和其他重要领导职务都起到了重要作用。在上一个周期中，美国和SA之间的培训，研究和指导的连续性已经走向平等的美国和南非之间的伙伴关系，但仍需要做更多的事情，尤其是随着培训的治疗准备和治疗计划评估的挑战变得更加直接。 该计划在当前周期中的重点将是确定南非现有研究中心的关键差距，并招募和导师适当的热情，明亮的年轻和成熟的中级研究人员为他们提供大型临床试验的设计和行为所需的知识库和技能（ESP疫苗和小杀剂）；发病机理研究，对HIV/TB相互作用的研究以及ARV治疗影响的评估。目的是加强并扩大南非独立HIV相关研究团队的数量；加强了南非承担更多国家和地区培训需求的能力，并发展了运营，实施和监测艾滋病治疗的南非规模所需的技能。 在对培训优先级的持续评估以及对美国-SA科学咨询委员会的仔细监督下的指导下，我们将继续在美国和南非提供适当的短期到中等和长期培训机会。将优先考虑公认的艾滋病研究小组的受训者。付出巨大的努力将用于均衡美国和南非之间的培训机会。这包括在南非建立一项高质量的流行病学硕士课程，最初是由美国和南非教师共同教授的。由NIH，CDC和其他人资助的丰富的艾滋病和结核病项目为受训者提供了各种培训和研究机会。总体而言，该计划旨在增加南非独立既定的艾滋病和结核病研究人员的数量，以便在未来的国内指导和培训中有当地的关键质量。尽管这是一个长期的目标，但拟议的计划设定了有关该任务的良好手持，并在过去五年中汲取了最有价值的教训，例如持续的国内指导，指导和支持，助学金写作以及招募已经在生产研究小组中的候选人的重要性。