Cognitive Processes, PTSD, and Alcohol Use

描述(申请人提供)：共病的创伤后应激障碍和酒精使用障碍是常见的和虚弱的，因此，识别与其发展相关的因素是非常重要的。研究结果支持自我用药假说来解释这种共病。然而，解释酒精用于创伤后应激障碍自我治疗的机制仍未得到解决。这项研究的主要目的是检验创伤事件后AUD的认知模型。该模型将创伤后应激障碍的认知加工理论与AUD发展模型结合起来，强调认知预期。这项研究将使用纵向设计，评估100名在创伤事件发生后1个月、3个月和6个月遭受身体或性侵犯的成年女性，以确定AUD是如何随着时间的推移而发展的，作为一般和创伤后应激障碍特定酒精结果预期、受创伤事件影响的认知和创伤后应激障碍症状严重程度的函数。目的1：检查创伤后1个月的一般酒精预期，作为酒精消费的预测因子，以及创伤后3个月创伤后应激障碍的酒精预期。目的2：检查创伤后1个月创伤后应激障碍的严重程度，作为创伤后3个月酒精消耗量和创伤后应激障碍特定酒精预期的预测因子。目的：评估创伤后1个月的同化和过度调节作为创伤后3个月创伤后应激障碍症状的预测因子。目的：评估酒精摄入量、创伤后应激障碍特有的酒精预期和创伤后3个月创伤后应激障碍的严重程度作为创伤后6个月酒精使用障碍的预测因子。

DESCRIPTION (provided by applicant): Co-morbid PTSD and alcohol use disorders are both common and debilitating, therefore, identification of factors related to their development is of great import. Research findings support a self-medication hypothesis to explain this comorbidity. Yet mechanisms explaining the use of alcohol for self-medication of PTSD remain unaddressed. The overarching purpose of this study is to examine a cognitive model of AUD following traumatic events. This model will integrate cognitive processing theory of PTSD with models for the development of AUD emphasizing cognitive expectancies. This study will use a longitudinal design, assessing 100 adult women with a physical or sexual assault one, three, and six months after the traumatic event to determine how AUD develop over time, as a function of general and PTSD-specific alcohol outcome expectancies, cognitions affected by the traumatic event, and severity of PTSD symptoms. Aim 1: Examine general alcohol expectancies 1 month post-trauma, as predictors of alcohol consumption, and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 2: Examine PTSD severity I month post-trauma, as a predictor of alcohol consumption and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 3: Evaluate assimilation and over-accommodation I month post-trauma as predictors of PTSD symptoms 3 months post-trauma. Aim 4: Evaluate alcohol consumption, PTSD-specific alcohol expectancies, and PTSD severity 3 months post-trauma as predictors of alcohol use disorders 6 months post-trauma.