Cognitive Processes, PTSD, and Alcohol Use

认知过程、创伤后应激障碍和饮酒

• 批准号: 6830778
• 负责人: DEBRA L KAYSEN
• 金额: $ 4.55万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6830778
• 关键词: alcoholic beverage consumption; alcoholism /alcohol abuse; behavior prediction; behavioral /social science research tag; clinical research; cognition; comorbidity; expectancy; female; human subject; postdoctoral investigator; posttraumatic stress disorder; self medication; sex abuse; violence

DESCRIPTION (provided by applicant): Co-morbid PTSD and alcohol use disorders are both common and debilitating, therefore, identification of factors related to their development is of great import. Research findings support a self-medication hypothesis to explain this comorbidity. Yet mechanisms explaining the use of alcohol for self-medication of PTSD remain unaddressed. The overarching purpose of this study is to examine a cognitive model of AUD following traumatic events. This model will integrate cognitive processing theory of PTSD with models for the development of AUD emphasizing cognitive expectancies. This study will use a longitudinal design, assessing 100 adult women with a physical or sexual assault one, three, and six months after the traumatic event to determine how AUD develop over time, as a function of general and PTSD-specific alcohol outcome expectancies, cognitions affected by the traumatic event, and severity of PTSD symptoms. Aim 1: Examine general alcohol expectancies 1 month post-trauma, as predictors of alcohol consumption, and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 2: Examine PTSD severity I month post-trauma, as a predictor of alcohol consumption and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 3: Evaluate assimilation and over-accommodation I month post-trauma as predictors of PTSD symptoms 3 months post-trauma. Aim 4: Evaluate alcohol consumption, PTSD-specific alcohol expectancies, and PTSD severity 3 months post-trauma as predictors of alcohol use disorders 6 months post-trauma.

描述（由申请人提供）：PTSD和酒精使用障碍的共病既常见又使人衰弱，因此，确定与它们发展相关的因素是非常重要的。研究结果支持自我用药假说来解释这种合并症。然而，解释使用酒精进行创伤后应激障碍自我药物治疗的机制仍未得到解决。本研究的主要目的是研究创伤性事件后AUD的认知模型。该模型将PTSD的认知加工理论与强调认知期望的AUD发展模型相结合。本研究将采用纵向设计，在创伤事件发生1、3和6个月后评估100名遭受身体或性侵犯的成年女性，以确定AUD如何随着时间的推移发展，作为一般和创伤后应激障碍特异性酒精结果预期的功能，受创伤事件影响的认知，以及创伤后应激障碍症状的严重程度。目的1：检查创伤后1个月的一般酒精预期，作为酒精消费的预测因子，以及创伤后3个月的ptsd特异性酒精预期。目的2：检查创伤后1个月的创伤后应激障碍严重程度，作为创伤后3个月饮酒和创伤后应激障碍特异性酒精预期的预测因子。目的3：评估创伤后1个月的同化和过度适应作为创伤后3个月PTSD症状的预测因素。目的4：评估酒精消费、PTSD特异性酒精预期和创伤后3个月PTSD严重程度作为创伤后6个月酒精使用障碍的预测因子。