Cognitive Processes, PTSD, and Alcohol Use

描述（由申请人提供）：创伤后应激障碍（PTSD）和酒精使用障碍并存是常见且令人衰弱的，因此，识别与其发展相关的因素至关重要。研究结果支持自我药疗假说来解释这种合并症。然而，解释使用酒精自我治疗PTSD的机制仍然没有得到解决。本研究的主要目的是研究创伤性事件后AUD的认知模型。该模型将PTSD的认知加工理论与强调认知期望的AUD发展模型相结合。这项研究将采用纵向设计，评估100名成年女性在创伤事件发生后1个月、3个月和6个月遭受身体或性侵犯，以确定AUD如何随时间发展，作为一般和PTSD特异性酒精结果预期、受创伤事件影响的认知和PTSD症状严重程度的函数。目标1：检查创伤后1个月的一般酒精预期，作为酒精消费的预测因子，以及创伤后3个月的PTSD特异性酒精预期。目的2：检查创伤后1个月的PTSD严重程度，作为创伤后3个月饮酒和PTSD特异性酒精预期的预测因子。目的3：评估创伤后1个月同化和过度调节作为创伤后3个月PTSD症状的预测因子。目标4：评估创伤后3个月的饮酒量、创伤后应激障碍特异性酒精预期和创伤后应激障碍严重程度，作为创伤后6个月酒精使用障碍的预测因素。

DESCRIPTION (provided by applicant): Co-morbid PTSD and alcohol use disorders are both common and debilitating, therefore, identification of factors related to their development is of great import. Research findings support a self-medication hypothesis to explain this comorbidity. Yet mechanisms explaining the use of alcohol for self-medication of PTSD remain unaddressed. The overarching purpose of this study is to examine a cognitive model of AUD following traumatic events. This model will integrate cognitive processing theory of PTSD with models for the development of AUD emphasizing cognitive expectancies. This study will use a longitudinal design, assessing 100 adult women with a physical or sexual assault one, three, and six months after the traumatic event to determine how AUD develop over time, as a function of general and PTSD-specific alcohol outcome expectancies, cognitions affected by the traumatic event, and severity of PTSD symptoms. Aim 1: Examine general alcohol expectancies 1 month post-trauma, as predictors of alcohol consumption, and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 2: Examine PTSD severity I month post-trauma, as a predictor of alcohol consumption and PTSD-specific alcohol expectancies 3 months post-trauma. Aim 3: Evaluate assimilation and over-accommodation I month post-trauma as predictors of PTSD symptoms 3 months post-trauma. Aim 4: Evaluate alcohol consumption, PTSD-specific alcohol expectancies, and PTSD severity 3 months post-trauma as predictors of alcohol use disorders 6 months post-trauma.