How does iron accumulation affect Parkinson’s disease and what controls it?

铁积累如何影响帕金森病以及如何控制它？

• 批准号: nhmrc : 1066925
• 负责人: A/Pr Jason Howitt
• 金额: $ 36.38万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-iron-accumulation-controls-it/455270
• 关键词: How; does; iron; accumulation; affect

Currently there is no cure for Parkinson's disease, and although we have a number of treatments to manage the disease there is an urgent need for a further understanding of the disease process. This proposal will investigate the critical role that iron plays in the cause of neuronal cell death that results in Parkinson's disease, and will investigate methods for regulating metal levels in the brain.

目前还没有治愈帕金森氏症的方法，尽管我们有许多治疗方法来管理这种疾病，但迫切需要进一步了解疾病的过程。这项建议将调查铁在导致帕金森氏症的神经细胞死亡原因中所起的关键作用，并将研究调节大脑中金属水平的方法。