Targeting autism with macrocephaly using mechanism based therapeutics

使用基于机制的疗法治疗大头畸形自闭症

• 批准号: nhmrc : GNT1129717
• 负责人: A/Pr Jason Howitt
• 金额: $ 83.17万
• 依托单位: Swinburne University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/targeting-autism-macrocephaly-based-therapeutics/1347771
• 关键词: Targeting; autism; macrocephaly; using; mechanism

Autism affects a large number of children in our community and currently there is a lack of any medication to treat its core pathology. In this grant we will study the underlying biochemical changes in the brain that result in autism through the development of a new mouse model of the disorder. This mouse model will then be used test drugs to identify therapeutic targets for the treatment of autism.

自闭症影响了我们社区的大量儿童，目前缺乏任何治疗其核心病理的药物。在这笔赠款中，我们将通过开发一种新的自闭症小鼠模型来研究导致自闭症的大脑潜在的生化变化。然后，这个小鼠模型将被用于测试药物，以确定治疗自闭症的治疗靶点。