LSU DENTAL COBRE: STATISTICAL CORE

统计核心的总体使命是在研究设计、样本量估计/统计功效分析、统计方法和COBRE项目数据库管理等领域提供支持。通过统计核心发展和实施服务是中心取得全面成功的关键。统计核心不仅在提供统计服务方面，而且在促进初级主要研究者（JPI）的指导过程中发挥着至关重要的作用，以培养他们对研究设计和数据分析重要性的理解。统计核心将为COBRE PI和中心成员提供：1。研究设计、样本量估算、统计分析计划、研究方案咨询。2.开发和管理数据库管理系统和质量控制程序。3.研究数据的统计分析，结果的呈现和解释。4.提供教育服务，以支持研究者在研究设计和分析方面的发展。5.加强统计核心服务，使COBRE具备最先进的能力。统计核心将支持COBRE所有项目的研究工作。安全的基于网络的数据输入界面将允许使用SAS IntrNet（R）软件从笔记本电脑输入椅子旁的数据。核心人员将与研究者密切合作，以确保及时、准确和有效地收集和分析研究数据。除了管理研究数据的收集和储存外，核心还将负责数据分析、解释和研究结果的展示。核心小组还将协助数据监测委员会编写报告、摘要和分析，供会议审查和中期分析。

The overall mission of the Statistical Core is to provide support in the areas of study design, sample size estimation/statistical power analysis, statistical methodology and database management for the projects in the COBRE. The development and implementation of services through the Statistical Core is key to the overall success of the Center. The Statistical Core has a crucial role in not only providing statistical services but in contributing to the mentoring process for the junior Principal Investigators (JPIs) in developing their understanding of the importance of study design and data analysis. The Statistical Core will provide the COBRE PIs and members of the Center with: 1. Consultation on study design, sample size estimation, statistical analysis plan, and research proposal. 2. Development and management of database management system and quality control procedures. 3. Statistical analysis of study data, presentation and interpretation of results. 4. Educational services to support investigator development in study design and analysis. 5. Enhancement of statistical core services to bring state of the art capabilities to the COBRE. The Statistical Core will support research efforts for all COBRE projects. Secure web-based data entry interfaces will allow chair-side data entry from a laptop computer using SAS IntrNet (R) software. The core will work closely with investigators to ensure timely, accurate, and efficient collection and analysis of study data. In addition to managing the collection and storage of study data, the core will be responsible for data analysis, interpretation and presentation of study results. The core will also assist the data monitoring committees by preparing reports, summaries and analyses for review at meetings and interim analyses.