LSU DENTAL COBRE: STATISTICAL CORE

路易斯安那州立大学牙科 COBRE：统计核心

• 批准号: 7610698
• 负责人: Donald E Mercante
• 金额: $ 18.21万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610698
• 关键词: Area; Arts; Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Consultations; Data; Data Analyses; Database Management Systems; Databases; Dental; Development; Epidemiology; Feedback; Funding; Grant; Institution; Mentors; Methodology; Mission; Pilot Projects; Principal Investigator; Procedures; Process; Quality Control; Recruitment Activity; Research; Research Design; Research Personnel; Research Proposals; Resources; Role; Sample Size; Services; Smoking; Source; Statistical Methods; Support of Research; United States National Institutes of Health; Work; design; statistical service; statistics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Introduction: The overall mission of the Statistical Core is to provide support in the areas of study design, sample size estimation/statistical power analyses, statistical methodology and database management for the projects in the COBRE. The Statistical Core has a crucial role in not only providing statistical services but in contributing to the mentoring process for the junior principal investigators (JPIs) in developing their understanding of the importance of study design and data analysis. Objective: The activities of the Statistical Core are guided by the following 5 specific aims. (1) Consultation with Junior Principle Investigators (JPIs) on study design, sample size estimation, statistical analysis plan, and research proposal. (2) Development and management of database management system and quality control procedures. (3) Statistical analysis of study data, presentation and interpretation of results. (4) Educational services to support investigator development in study design and analysis. (5) Enhancement of statistical core services to bring state of the art capabilities to the COBRE. Methods: The Statistical Core actively recruited for an M.S. level biostatistician. Each project JPI met one on one with the Statistical Core PI to discuss study issues. Essential computing needs to support the research efforts of the COBRE were identified. We met with the EAC and received valuable feedback. Results: The Statistical Core successfully recruited an statistician. Dr.s Mercante and Simonsen presented seminars to the JPIs on design and analysis issues in statistics and epidemiology, respectively. A database has been developed for Dr. Leighs project. We assisted Dr. Porter-Williams in designing a pilot study. We worked with Dr. Vastardis to resolve the issue of smoking. We purchased and installed a new server. Discussion: The Statistical Core has made significant progress towards the stated objectives and will continue to work closely with the JPIs to provide guidance and support for their research.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 简介：统计核心的总体使命是在研究设计、样本量估计/统计功效分析、统计方法和COBRE项目数据库管理等领域提供支持。统计核心不仅在提供统计服务方面，而且在促进初级主要研究者（JPI）对研究设计和数据分析重要性的理解方面发挥着至关重要的作用。 目标：统计核心的活动以下列5个具体目标为指导。(1)与初级主要研究者（JPI）就研究设计、样本量估计、统计分析计划和研究提案进行协商。(2)开发和管理数据库管理系统和质量控制程序。(3)研究数据的统计分析，结果的呈现和解释。(4)提供教育服务，以支持研究者在研究设计和分析方面的发展。(5)加强统计核心服务，使COBRE具备最先进的能力。 方法：统计核心积极招募一个M.S.一级生物统计师。每个项目JPI与统计核心PI一对一会面，讨论研究问题。 确定了支持COBRE研究工作的基本计算需求。我们会见了选管会，并收到了宝贵的反馈意见。 结果：统计核心成功招募了一名统计员。Mercante博士和Simonsen博士分别就统计学和流行病学的设计和分析问题向JPI介绍了研讨会。已经为利博士建立了一个数据库的项目。我们协助Porter-Williams博士设计了一项试点研究。我们与Vastardis博士合作解决吸烟问题。我们购买并安装了新的服务器。 讨论内容：统计核心在实现既定目标方面取得了重大进展，并将继续与联合指标机构密切合作，为它们的研究提供指导和支持。