Construction - Chronic Disease Clinical Research Center

建设-慢性病临床研究中心

• 批准号: 7898503
• 负责人: DAVID I MEYER
• 金额: $ 971.18万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-25 至 2013-03-24
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7898503
• 关键词: Aging; Area; Atherosclerosis; Biomedical Research; Cardiac; Chronic Disease; Chronic Obstructive Airway Disease; Clinic; Clinical Research; Collaborations; Commit; Communities; Diagnostic; Ensure; Environment; Equipment; Exercise Physiology; Funding; Goals; Grant; HIV; Housing; Laboratories; Laboratory Research; Lead; Los Angeles; Medical center; Occupations; Outpatients; Participant; Patients; Pharmacy facility; Reading; Records; Research; Research Activity; Research Institute; Research Personnel; Specimen Handling; Structure; Technology; TimeLine; Training; Translational Research; United States National Institutes of Health; X-Ray Computed Tomography; ethnic minority population; high standard; meetings; programs; pulmonary function; repaired; square foot

DESCRIPTION (provided by applicant): The goal of the proposed research construction project is to provide an optimal environment at Los Angeles Biomedical Research Institute (LA BioMed) in which to conduct collaborative, interdiscliplinary, translational research in chronic diseases. We propose the construction of a 2-story, 23,171 sq ft building (2,153 m2) Chronic Disease Clinical Research Center (CDCRC) which will consolidate the collaborative research programs of multiple investigator groups who are studying chronic diseases, including atherosclerosis, chronic obstructive pulmonary disease (COPD) and HIV. LA BioMed, founded in 1953, is an independent, non-profit research institute with $60-$70 million in annual grant funding. Located on the 72-acre grounds of Harbor-UCLA Medical Center (HUMC), the majority of the LA BioMed research programs are housed in 66-year old deteriorating wooden barracks. These aging structures are scattered and beyond repair, and are not conducive to scientific collaboration, expansion of research activities or providing an environment suited for research participants. The continued use of these barracks makes it difficult to attract and retain successful investigators. Over the past 20 years, four new research buildings have been constructed but space in these modern facilities is limited. Although more than 60% of LA BioMed grant funding supports clinical research, there is a severe shortage of modern, clinical research areas. The proposed CDCRC will be located within the LA BioMed Research Park and will include space for investigators and research personnel; outpatient research clinic with dedicated patient parking; research pharmacy; specimen processing laboratory and storage; cardiac CT (computerized tomography) reading center; exercise physiology, pulmonary function and cardiac laboratories; research records storage; and a meeting room to conduct patient and staff training sessions. Included with this proposal are fixed equipment items that are needed to support the facility, including two biosafety cabinets and wall-mounted exam room diagnostic sets. Non-fixed equipment is either currently available or will be procured by LA BioMed. The CDCRC will allow investigators who study chronic diseases to expand their clinical research activities, provide promising new treatments and therapies to an underserved ethnic minority community, and contribute to the translational research agenda locally and nationally. The new facility will stimulate the research environment at LA BioMed, allow for the transition of federally-funded investigators into modern research buildings, serve as a focus for recruitment of new researchers and trainees, and lead to jobs creation during the construction period and beyond. LA BioMed is fully committed to ensuring that the building is constructed according to NIH specifications, within the prescribed timeline and with the highest standards for green, sustainable technology.

描述（由申请人提供）：拟议的研究建设项目的目标是在洛杉矶生物医学研究所（LA BioMed）提供一个最佳的环境，在其中进行合作，跨学科，慢性疾病的转化研究。我们建议建造一座2层楼高，23，171平方英尺（2，153平方米）的慢性病临床研究中心（CDCRC），该中心将巩固正在研究慢性病（包括动脉粥样硬化，慢性阻塞性肺疾病（COPD）和HIV）的多个研究小组的合作研究计划。 LA BioMed成立于1953年，是一家独立的非营利研究机构，每年获得6000万至7000万美元的资助。洛杉矶生物医学研究中心位于加州大学洛杉矶分校海港医学中心（HUMC）的72英亩土地上，大部分研究项目都位于66年历史的破旧木制营房中。这些老化的结构分散且无法修复，不利于科学合作，扩大研究活动或提供适合研究参与者的环境。继续使用这些营房，很难吸引和留住成功的调查员。在过去的20年里，已经建造了四座新的研究大楼，但这些现代化设施的空间有限。虽然超过60%的LA BioMed拨款支持临床研究，但现代临床研究领域严重短缺。拟议的CDCRC将位于洛杉矶生物医学研究园区内，包括研究者和研究人员的空间;门诊研究诊所，专用患者停车场;研究药房;标本处理实验室和储存;心脏CT（计算机断层扫描）阅读中心;运动生理学、肺功能和心脏实验室;研究记录存储;以及一个会议室，用于进行患者和工作人员培训课程。本提案包括支持该设施所需的固定设备项目，包括两个生物安全柜和壁挂式检查室诊断仪。非固定设备目前可用或将由LA BioMed采购。 CDCRC将允许研究慢性病的研究人员扩大他们的临床研究活动，为服务不足的少数民族社区提供有前途的新治疗和疗法，并为当地和国家的转化研究议程做出贡献。新设施将刺激LA BioMed的研究环境，允许联邦资助的研究人员过渡到现代化的研究大楼，作为招聘新研究人员和学员的重点，并在施工期间及以后创造就业机会。LA BioMed完全致力于确保建筑物的建造符合NIH的规范，在规定的时间轴内，并具有绿色，可持续技术的最高标准。