EXTRAMURAL RESEARCH FACILITIES PROGRAM

校外研究设施计划

• 批准号: 7000790
• 负责人: Daniel Michael Dorsa
• 金额: $ 399.95万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-20 至 2014-10-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000790
• 关键词: Extramural Activities; programs; research facility

DESCRIPTION (provided by applicant): Oregon Health & Science University (OHSU) seeks funds to construct new outdoor group housing and a clinic and hospital support facility at the Oregon National Primate Research Center (ONPRC). The proposed outdoor group housing will be called the Primate Enclosures in a Natural Setting (PENS). Rapid research growth, expansion of Specific Pathogen Free (SPF) breeding colonies, and compliance with the USDA "Draft Policy on Environment Enhancement for Nonhuman Primates" necessitate additional social housing for nonhuman primates (NHPs) and increased animal central support space. Our long-term objectives are to: 1) provide housing for NHPs in social groups in a natural setting; 2) protect growing populations of SPF Indianorigin rhesus macaques; 3) free-up cage space for the growing number of research projects; and 4) provide state-of-the-art central clinic and hospital support facilities to benefit all NHPs at ONPRC. To accomplish these objectives, we are proposing to construct outdoor group housing, called PENS, to provide a natural setting in which to raise NHPs in social groups and to accommodate the need for expansion of the SPF Indian-origin rhesus macaques, which are an invaluable resource for biomedical research. The design incorporates innovative features that will offer animals multiple environmental choices. Each PENS will consist of a 2,021 NSF grassy Outdoor Area Enclosure to simulate a natural setting and a 478 NSF Enclosed Area Shelter that provides excellent protection against inclement weather and also serves as a feed and catch area. Each of the 6 individual PENS will provide housing for 40 - 60 rhesus monkeys. We are also proposing to construct an important and much needed Clinic and Hospital Support Facility located adjacent to the six PENS. This will add an additional 80 cages to the current 60-cage clinic located on the opposite side of the campus. Specific Aim 1: Construct 6 PENS for SPF rhesus macaque breeding colonies. Providing a heated Enclosed Area Shelter connected to a large grassy Outdoor Area Enclosure is thought to be the best means possible for the ONPRC to raise healthy, naturally enriched SPF rhesus macaques. Specific Aim 2: Construct a 2,344 NSF Clinic and 80-cage Hospital Support Facility adjacent to the proposed PENS (Specific Aim 1) to provide much needed clinical/support space. In addition to providing medical facilities for up to 360 rhesus to be housed in the six PENS, it will also provide much needed hospital support space for the approximately 1,000 rhesus located in corrals adjacent to the proposed PENS site.

描述（由申请人提供）： 俄勒冈州健康与科学大学（OHSU）寻求资金，在俄勒冈州国家灵长类动物研究中心（ONPRC）建造新的户外团体住房和诊所和医院支持设施。拟议中的户外群体住房将被称为自然环境中的灵长类动物围栏（PENS）。快速的研究增长，无特定病原体（SPF）繁殖群的扩大，以及遵守美国农业部“非人灵长类动物环境改善政策草案”，需要为非人灵长类动物（NHP）提供额外的社会住房，并增加动物中心支持空间。我们的长期目标是：1）在自然环境中为社会群体中的NHP提供住房; 2）保护不断增长的SPF印度恒河猴种群; 3）为越来越多的研究项目腾出笼子空间;以及4）提供最先进的中心诊所和医院支持设施，使ONPRC的所有NHP受益。为了实现这些目标，我们建议建造户外团体住房，称为PENS，以提供一个自然的环境，在其中提高NHP的社会群体，并适应SPF印度原产恒河猴，这是生物医学研究的宝贵资源的扩展的需要。该设计融合了创新功能，为动物提供多种环境选择。每个PENS将包括一个2,021 NSF草地室外区域围栏，以模拟自然环境和一个478 NSF封闭区域庇护所，提供良好的保护，免受恶劣天气的影响，也作为饲料和捕捞区。6个单独的PENS中的每一个将为40 - 60只恒河猴提供住房。此外，我们亦建议在6个永久性居民宿舍附近兴建一个重要和急需的诊所及医院支援设施。这将增加额外的80个笼子，以目前的60笼诊所位于校园的对面。 具体目标1：构建用于SPF恒河猴繁殖群的6个PENS。提供一个加热的封闭区域庇护所连接到一个大的草地户外区域围栏被认为是最好的手段，为ONPRC提高健康，自然丰富的SPF恒河猴。 具体目标二：在拟建的PENS（具体目标1）附近建造一个2，344 NSF诊所和80笼医院支持设施，以提供急需的临床/支持空间。除了为将安置在6个PENS中的多达360只恒河猴提供医疗设施外，它还将为位于拟建PENS场地附近的Corpus的约1，000只恒河猴提供急需的医院支持空间。