Conference Modeling of Protein Interactions in Genomes

基因组中蛋白质相互作用的会议建模

• 批准号: 7000500
• 负责人: SANDOR VAJDA
• 金额: $ 0.5万
• 依托单位: BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-06-15 至 2006-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7000500
• 关键词: genome; meeting /conference /symposium; protein protein interaction; protein structure; travel

DESCRIPTION (provided by applicant): Support is requested for the multidisciplinary conference MODELING OF PROTEIN INTERACTIONS IN GENOMES 2005, to be held on 24-27 June, 2005 in Lawrence, Kansas. The meeting will involve a combination of biological, physical, and computational scientists, and will focus on computational procedures for reconstruction and study of the networks of connections between proteins in genomes, including experimental studies, knowledge-based methods, sequence analysis, and structural approaches. The specific aims of the Modeling of Protein Interactions in Genomes Conference 2005 are as follows: (1) discussion of the structural aspects of protein interactions, including docking methods; (2) discussion of current and emerging methods of determining protein binding sites using both sequence-based and structure-based approaches; (3) modeling of protein-protein interactions on the basis of a diverse set of experimental techniques (e.g., mass spectroscopy, cryo-electron microscopy, cross-linking, NMR, etc); and (4) solving computational problems associated with the analysis of protein interaction networks from large-scale screening experiments (primarily two-hybrid essays and mass spectrometry). Experts from various areas of protein interactions were selected to serve on our Advisory Committee and also to present at the conference. Further presentations will be invited as well as selected by the Advisory Committee from the submitted abstracts. A poster session will be held on one of the conference days. The conference will be relatively small - approximately 100 participants. The organizers will pay special attention to attracting young investigators as speakers and poster presenters. We will encourage participation of students and postdoctoral fellows. An important aspect of the conference organization will be our effort to diversify the participation by attracting women and minority scientists. This will primarily achieved by contacting faculty members working in the areas of Biophysics and Biochemistry in minority-serving institutions.

描述（由申请人提供）：支持将于2005年6月24日至27日在堪萨斯劳伦斯举行的2005年基因组蛋白质相互作用的多学科会议建模。会议将涉及生物，物理和计算科学家的组合，并将重点放在重建和研究基因组中蛋白质之间的连接网络的计算程序，包括实验研究，基于知识的方法，序列分析和结构方法。2005年基因组蛋白质相互作用建模会议的具体目标如下：（1）讨论蛋白质相互作用的结构方面，包括对接方法;（2）讨论使用基于序列和基于结构的方法确定蛋白质结合位点的现有和新兴方法;（3）基于不同的实验技术（例如，质谱、低温电子显微镜、交联、NMR等）;以及（4）解决与来自大规模筛选实验（主要是双杂交论文和质谱）的蛋白质相互作用网络的分析相关的计算问题。 来自蛋白质相互作用各个领域的专家被选为我们的咨询委员会成员，并出席会议。咨询委员会将邀请并从提交的摘要中挑选更多的专题介绍。将在其中一个会议日举行海报会议。会议规模相对较小，约100人。组织者将特别注意吸引年轻的调查人员作为演讲者和海报展示者。我们将鼓励学生和博士后研究员的参与。会议组织工作的一个重要方面将是我们通过吸引妇女和少数民族科学家，努力使与会者多样化。这将主要通过与少数民族服务机构中从事生物物理学和生物化学领域工作的教员联系来实现。