Computational approaches to noncoding RNAs

描述(由申请者提供)：我们打算组织一个题为“非编码RNA的计算方法”的研讨会。研讨会将于2006年7月16日至7月28日在西班牙贝纳斯克的贝纳斯克科学中心举行。研讨会将着重讨论用于发现和表征功能和调控RNA的计算方法。 这次研讨会的主要目标是将RNA信息学领域的领先者聚集在一起。这个 参与者将主要是计算生物学家，他们已经在RNA生物信息学方面做出了重大贡献。我们将讨论该领域的需求，并将确定在不久的将来将塑造该领域的新方法和算法。讲习班将以在现场进行实际研究为导向。 主要讨论的主题是：(1)预测二维和三维RNA结构的算法。RNA功能的推断。(2)发现新的RNA基因的计算方法和对RNA基因进行系统基因组注释的工具。(3)RNA结构比对。(4)RNA同源搜索。如何通过考虑结构和序列信息来改进RNA相似性搜索。(5)基于RNA的系统发育方法。(6)ncRNA家族和RNA数据库。

DESCRIPTION (provided by applicant): We intend to organize a workshop entitled "Computational approaches to noncoding RNAs". The workshop will take place from July 16th to July 28th, 2006 at the Benasque Center for Sciences, Benasque, Spain. The workshop will have a strong focus on computational methods for the discovery and characterization of functional and regulatory RNAs. The main goal of this workshop is to bring together the leaders in the field of RNA informatics. The participants will be mostly computational biologists which have already shown significant contributions in RNA bioinformatics. We will discuss the needs of the field, and will identify the new methods and algorithms that will shape the field in the near future. The workshop will be oriented towards performing actual research on the site. The main topics of discussion will be: (1) Algorithms for the prediction of two and three dimensional RNA structures. Inference of RNA function. (2) Computational methods for the discovery of novel RNA genes and tools for the systematic genomic annotation of RNA genes. (3) RNA structural alignments. (4) RNA homology searches. How to improve RNA similarity searches by taking into account the structure as well as the sequence information. (5) RNA-based phylogenetic methods. (6) ncRNA families and RNA databases.