8th ASM Conference on Candida and Candidiasis

性状（由申请方提供）：白色念珠菌是一种寄生于皮肤和粘膜表面的真菌。它也是这些表面的机会性疾病以及内部传播疾病的媒介。虽然皮肤和粘膜表面的感染可能是显著发病的原因，并且每年影响数百万美国人，但它们不像播散性疾病那样危及生命。在20世纪80年代中期，越来越多的研究人员被吸引到疾病的发病机制的研究。为了满足这一群体之间交流思想的需要，1987年举行了第一届ASM念珠菌和念珠菌病会议，约有115人参加。从那时起，不仅研究人员的数量增加了，而且疾病患者的数量也增加了。口腔粘膜疾病是艾滋病的一种常见并发症，念珠菌已成为导致医院内血流感染的第四大原因。近年来，出现了唑类耐药菌株，非白念珠菌分离株的频率增加，特别是那些固有耐药的菌株。ASM念珠菌和念珠菌病会议自1987年以来每三年举行一次，自2002年以来每两年举行一次，是从事念珠菌感染生物学，流行病学和发病机制研究的研究人员的首要论坛。因此，第八次会议将于2006年3月13日至17日在丹佛凯悦酒店举行，第八次会议的目标是继续提供论坛，介绍最先进的研究和研究人员见面，并讨论他们的工作非正式。会议预计将有350-400名与会者，并展示200-250张海报。口头和/或海报会议的主题包括：环境感知和反应，流行病学和进化，主机响应和疾病模型，主机壁龛和微生物群落，Anticandidal代理，细胞壁和表面，细胞类型和形状。发言者和与会者预计将代表念珠菌研究人员的国际社会，既建立和新的调查人员以及学生和学员出席。许多发言者，包括学生和受训人员，将从摘要中选出。NIH通过各种研究所和方案，慷慨地支持了这次会议以及近年来会议的许多美国演讲者和与会者，希望NIH将再次加入ASM和私人来源，为2006年第8次会议提供财政援助。

DESCRIPTION (provided by applicant): Candida albicans is a commensal that colonizes skin and mucosal surfaces. It is also an agent of opportunistic disease of these surfaces as well as internal disseminated disease. While infections of cutaneous and mucosal surfaces may be a cause of significant morbidity and affect millions of Americans annually, they are not life threatening as is disseminated disease. In the mid 1980's a growing number of researchers were attracted to the study of pathogenesis of disease. In response to the need for exchange of ideas among this group, the first ASM Conference on Candida and Candidiasis was held in 1987 with an attendance of about 115 participants. Since this time not only have the number of researchers grown but so have the number of patients with disease. Oral mucosal disease is unfortunately a nearly universal complication of AIDS and Candida has now become the fourth leading cause of nosocomial blood stream infections. In recent years there has been an emergence of azole resistant strains and increased frequency of non-albicans isolates, particularly those that are inherently drug resistant. The ASM Conference on Candida and Candidiasis, held every three years since 1987 and every 2 years since 2002, is the premier forum for researchers engaged in study of the biology, epidemiology, and pathogenesis of candidal infection. Accordingly, the 8th Conference will be held March 13-17, 2006 at the Hyatt Regency in Denver, CO. The goal of the 8th Conference is to continue to provide the forum to present the state of the art research and for investigators to meet and discuss their work informally. The Conference is expected to have 350-400 attendees and the presentation of 200-250 posters. The topics for the oral and/or poster sessions include: Environmental Sensing and Responses, Epidemiology and Evolution, Host Response and Disease Models, Host Niches and Microbial Communities, Anticandidal Agents, Cell Wall and Surface, and Cell Type and Shape. Speakers and attendees are expected to represent the international community of Candida researchers with both established and new investigators as well as students and trainees present. Many of the speakers, including students and trainees, will be selected from abstracts. NIH through various institutes and programs has generously supported many of the American presenters and attendees of this conference, as well as the conferences in recent years, and it is hoped that NIH will again join ASM and private sources in providing financial assistance for the 8th Conference in 2006.