8th ASM Conference on Candida and Candidiasis

描述(申请人提供)：白色念珠菌是一种寄生在皮肤和粘膜表面的共生菌。它也是这些表面的机会性疾病以及内部播散性疾病的病原体。虽然皮肤和粘膜表面的感染可能是导致严重发病率的一个原因，每年影响数百万美国人，但它们并不像播散性疾病那样危及生命。20世纪80年代中期，S被越来越多的研究者吸引到疾病发病机制的研究中。针对这一群体之间交流意见的需要，1987年举行了第一次关于念珠菌和念珠菌病的会议，约有115人参加了会议。从那时起，不仅研究人员的数量增加了，疾病患者的数量也增加了。不幸的是，口腔粘膜疾病是艾滋病的一种几乎普遍的并发症，念珠菌现在已成为医院内血流感染的第四大原因。近年来，出现了对唑类耐药菌株，非白念珠菌菌株的出现频率增加，特别是那些天生耐药的菌株。关于念珠菌和念珠菌病的ASM会议自1987年以来每三年举行一次，自2002年以来每两年举行一次，是从事念珠菌感染的生物学、流行病学和发病机制研究的研究人员的主要论坛。因此，第8届大会将于2006年3月13日至17日在科罗拉多州丹佛市的凯悦酒店举行。第8届会议的目标是继续提供论坛，介绍最先进的研究成果，并让研究人员非正式地会面和讨论他们的工作。会议预计将有350-400人参加，并发布200-250张海报。口头和/或海报会议的主题包括：环境感知和反应、流行病学和进化、宿主反应和疾病模型、宿主生态位和微生物群落、抗真菌制剂、细胞壁和表面以及细胞类型和形状。演讲者和与会者预计将代表念珠菌研究人员的国际社会，既有现有的和新的研究人员，也有出席的学生和受训人员。许多演讲者，包括学生和实习生，将从摘要中挑选出来。美国国立卫生研究院通过各种研究所和项目，慷慨地支持了本次会议和近年来的会议的许多美国演讲者和与会者，并希望国家卫生研究院再次与ASM和私人来源一起，为2006年的第8届会议提供财政援助。

DESCRIPTION (provided by applicant): Candida albicans is a commensal that colonizes skin and mucosal surfaces. It is also an agent of opportunistic disease of these surfaces as well as internal disseminated disease. While infections of cutaneous and mucosal surfaces may be a cause of significant morbidity and affect millions of Americans annually, they are not life threatening as is disseminated disease. In the mid 1980's a growing number of researchers were attracted to the study of pathogenesis of disease. In response to the need for exchange of ideas among this group, the first ASM Conference on Candida and Candidiasis was held in 1987 with an attendance of about 115 participants. Since this time not only have the number of researchers grown but so have the number of patients with disease. Oral mucosal disease is unfortunately a nearly universal complication of AIDS and Candida has now become the fourth leading cause of nosocomial blood stream infections. In recent years there has been an emergence of azole resistant strains and increased frequency of non-albicans isolates, particularly those that are inherently drug resistant. The ASM Conference on Candida and Candidiasis, held every three years since 1987 and every 2 years since 2002, is the premier forum for researchers engaged in study of the biology, epidemiology, and pathogenesis of candidal infection. Accordingly, the 8th Conference will be held March 13-17, 2006 at the Hyatt Regency in Denver, CO. The goal of the 8th Conference is to continue to provide the forum to present the state of the art research and for investigators to meet and discuss their work informally. The Conference is expected to have 350-400 attendees and the presentation of 200-250 posters. The topics for the oral and/or poster sessions include: Environmental Sensing and Responses, Epidemiology and Evolution, Host Response and Disease Models, Host Niches and Microbial Communities, Anticandidal Agents, Cell Wall and Surface, and Cell Type and Shape. Speakers and attendees are expected to represent the international community of Candida researchers with both established and new investigators as well as students and trainees present. Many of the speakers, including students and trainees, will be selected from abstracts. NIH through various institutes and programs has generously supported many of the American presenters and attendees of this conference, as well as the conferences in recent years, and it is hoped that NIH will again join ASM and private sources in providing financial assistance for the 8th Conference in 2006.