Ambulatory Sternal Skin Conductance Recording Tool

动态胸骨皮肤电导记录工具

• 批准号: 7012037
• 负责人: GARY D HAVEY
• 金额: $ 25万
• 依托单位: ADVANCED MEDICAL ELECTRONICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2007-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7012037
• 关键词: androgen inhibitor; bioengineering /biomedical engineering; biomedical equipment development; clinical biomedical equipment; clinical research; computer program /software; drug adverse effect; electrical conductance; hot flash; human subject; miniature biomedical equipment; patient monitoring device; portable biomedical equipment; postmenopause; semiconduction; skin circulation; thorax; vasomotion

DESCRIPTION (provided by applicant): Advanced Medical Electronics Corporation proposes to develop a small, light-weight ambulatory sternal skin conductance measurement and recording tool for monitoring hot flashes in research studies. Packaging for the proposed tool is based on an electrocardiograph (ECG) system used for long-term cardiac monitoring. The application lessons and much of the literal technology of ambulatory ECG instruments are directly applicable to the proposed device. The proposed sternal skin conductance recording tool will be about the size of a digital wristwatch and will be designed to not interfere with daily life activities. It will record to solid state non-volatile (flash) memory for a minimum of 4 weeks between battery changes. The tool will have two short leads to sternum electrodes. The electronics module will be worn on the sternum and held in place using an adhesive patch. Collected data will be downloadable to a PC or other host computer via a simple USB interface cable. The proposed project will create an easy to use software application to review, archive, process, and experiment with the recorded data files. Laboratory and ambulatory evaluations will be completed on a prototype system by researchers at the Mayo Clinic in Rochester, MN. The objective of the phase I project is to evaluate the feasibility of developing a low-cost, reliable, ambulatory sternal skin conductance measurement and recording tool. A prototype device and companion software package will be designed, built, and evaluated, and a phase II production plan will be completed.

描述（由申请人提供）：高级医学电子公司建议开发一种小型，轻质的腹膜胸骨电导测量和记录工具，用于监测研究研究中的潮热。该工具的包装基于用于长期心脏监测的心电图（ECG）系统。应用课程和门诊心电图仪器的许多文字技术直接适用于拟议的设备。拟议的胸骨电导记录工具将大约是数字手表的大小，并且设计为不干扰日常生活活动。它将记录到固态非易失性（Flash）内存之间的至少4周之间的电池更换。该工具将有两个短的胸骨电极引线。电子模块将戴在胸骨上，并使用粘合剂贴在位。收集的数据将通过简单的USB接口电缆下载到PC或其他主机计算机。拟议的项目将创建一个易于使用的软件应用程序来查看，存档，过程和对记录的数据文件进行实验。明尼苏达州罗切斯特的梅奥诊所的研究人员将在原型系统上完成实验室和门诊评估。第一阶段项目的目的是评估开发低成本，可靠，卧床胸骨的皮肤电导测量和记录工具的可行性。将设计，构建和评估原型设备和配套软件包，并将完成II期生产计划。

项目成果

Sternal skin conductance: a reasonable surrogate for hot flash measurement?

胸骨皮肤电导：潮热测量的合理替代品？

• DOI: 10.1097/gme.0b013e31828cec53
• 发表时间: 2013
• 期刊: Menopause (New York, N.Y.)
• 作者: Pachman,DeirdreR;Loprinzi,CharlesL;Novotny,PaulJ;Satele,DanielV;Linquist,BreannaM;Wolf,Sherry;Barton,DebraL
• 通讯作者: Barton,DebraL