Postgraduate Training in Pediatric Oncology

描述（由申请人提供）：科罗拉多大学健康科学中心（UCHSC）和丹佛儿童医院的儿科肿瘤学奖学金计划拥有30多年的杰出历史。1993年，大量新的资源专门用于该计划的发展，导致建立了骨髓移植单位，神经肿瘤服务和基础科学家核心小组。此外，扩大了研究金方案，研究员有机会在UCHSC系统的任何实验室进行研究。该培训方案于2000年获得T32赠款的资助，目前提交的文件是这一支持的竞争性延续。目前24培训学院代表了广泛的科学学科，包括细胞周期控制和信号传导，转录调控和剪接，病毒学和免疫学。这些不同的学科和方法是统一的分子方法来解决基本的生物学问题，并通过它们的适用性，在肿瘤学研究的问题。由于临床经验的广度，儿童医院良好的临床声誉，以及新的研究机会，奖学金候选人自1993年以来一直在质量和奉献精神的学术生涯不断增加。事实上，自1993年以来，19名毕业生中有15人现在担任学术教师职务。研究金的最短期限为三年，第一年专门进行临床培训。目前有11名研究员在该计划中，他们都已经完成了他们的儿科住院医师，与8目前在研究培训超出他们的第一个临床研究员年。该提案旨在为那些选择在奖学金的第二年及随后几年从事儿科肿瘤学相关研究的研究员提供资金。因此，历史和最近的发展标志着这个培训计划是全国最好的培训计划之一。

DESCRIPTION (provided by applicant): The Pediatric Oncology Fellowship Program at the University of Colorado Health Sciences Center (UCHSC) and Denver Children's Hospital, has a distinguished history spanning over 30 years. In 1993, substantial new resources were dedicated to the development of this Program, leading to the establishment of a Bone Marrow Transplant unit, Neuro-oncology service, and a core group of basic scientists. In addition, the fellowship program was expanded and fellows were given the opportunity to perform research in any laboratory in the UCHSC system. The training program was funded in 2000 with this T32 grant, and the current submission is the competing renewal of this support. Presently 24 Training Faculty represent a broad range of scientific disciplines including cell cycle control and signaling, transcriptional regulation and splicing, virology, and immunology. These diverse disciplines and approaches are unified by use of molecular approaches to address fundamental biological questions, and by their applicability to problems in oncology research. Because of the breadth of the clinical experience, the fine clinical reputation of the Children's Hospital, and the new research opportunities available, fellowship candidates since 1993 have consistently increased in quality and dedication to an academic career. Indeed, 15 of 19 graduates since 1993 are now in academic faculty positions. The minimal fellowship duration is three years, with the first year exclusively clinical training. Currently there are 11 fellows in the Program, all of whom have previously completed their Pediatric residencies, with 8 currently in research training beyond their first clinical fellowship year. This proposal seeks funding for those fellows who elect to pursue research related to Pediatric Oncology in the second and subsequent years of the fellowship. Both history and recent developments thus mark this training program as one of the best in the nation.