课题基金 / 基金详情

HEALTHY AGING AND SENILE DEMENTIA

HEALTHY AGING AND SENILE DEMENTIA
健康老龄化和老年痴呆症
批准号:
7377176
负责人:
DAVID M. HOLTZMAN
金额:
$3.04万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-04-01 至 2007-03-31

项目摘要

项目成果

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In this study, we are trying to determine whether a subject's apoE genotype influences CNS lipid and cholesterol metabolism as well as its influence on the amyloid beta protein. The amyloid beta protein is felt to play an important role in Alzheimer's disease pathogenesis.
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会议论文
Cerebral amyloid angiopathy: Role of ApoE, innate immunity, and meningeal lymphatics
  • 批准号:
    10674679
  • 项目类别:
  • 资助金额:
    $62.0万
  • 财政年份:
    2022
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
APOE effects on glial lipid metabolism and 25-hydroxycholesterol: Effects on aging and AD-related pathology
  • 批准号:
    10667466
  • 项目类别:
  • 资助金额:
    $53.02万
  • 财政年份:
    2021
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
APOE effects on glial lipid metabolism and 25-hydroxycholesterol: Effects on aging and AD-related pathology
  • 批准号:
    10407944
  • 项目类别:
  • 资助金额:
    $54.01万
  • 财政年份:
    2021
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
Administration Core
  • 批准号:
    10622634
  • 项目类别:
  • 资助金额:
    $80.27万
  • 财政年份:
    2020
  • 负责人:
    DAVID M. HOLTZMAN
  • 依托单位:
海外基金