Brief Psychosocial Intervention for Head and Neck Cancer Patients and Partners

针对头颈癌患者及其伴侣的简短心理社会干预

• 批准号: 7226843
• 负责人: DONNA M POSLUSZNY
• 金额: $ 7.43万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-29 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7226843
• 关键词: clinical research; coping; emotions; head; head /neck neoplasm; neoplasm /cancer; quality of life; spouses

The proposed pilot research is in response to one of NCI's goals of this program announcement, which is to examine both adverse and positive effects of cancer diagnosis and treatment on patients and families, and to develop and evaluate interventions to improve quality of life and decrease negative outcomes. This prospective, longitudinal project seeks to further our understanding of the psychosocial sequelae of head and neck cancer for both patients and their partners or spouses, using both quantitative and qualitative methods, and to develop and test the feasibility of a brief couples intervention designed to improve the couples' well-being, quality of life, and relationship. The uncertainty and life threatening nature of cancer diagnoses can lead to anxiety, depression, and traumatic stress. Further, head and neck cancer is a physically and emotionally devastating disease that can cause facial disfigurement, as well as difficulties with speech, eating, and mobility. This results in poor quality of life. Spouses of patients also experience distress, caregiver burden, and decreases in their own quality of life. Although behavioral medicine interventions designed to improve psychological adjustment and quality of life in cancer patients have shown promising outcomes, head and neck cancer has been understudied in this context and there has been little research on including spouses in the intervention, or targeting the relationship for intervention. The specific aims of the proposed research are to (1) characterize both negative and positive symptoms of adjustment to head and neck cancer in patients and their partners over time, and to examine the psychosocial pathways in which relationship-focused coping and relationship quality may affect these symptoms. Negative symptoms include traumatic stress, depression, and anxiety and positive symptoms include enhanced growth and quality of life; (2) qualitatively examine the impact of head and neck cancer on patients, partners, and their relationship; and (3) to evaluate the feasibility of a brief two-session couples intervention to improve quality of life and relationship quality. Eighty couples (n=160) will be recruited. Distress, traumatic stress, positive outcomes, coping, relationship quality, and quality of life will be assessed in both patients and partners at one and six months after cancer diagnosis. Twenty of these couples will also participate in a qualitative interview. Ten additional couples will be recruited to test the feasibilty of the psychosocial intervention.

拟议的试点研究是对NCI计划公告的目标之一的回应，这是 检查癌症诊断和治疗对患者和家庭的不良和积极影响，以及 制定和评估干预措施以改善生活质量并减少负面结果。这 潜在的纵向项目旨在进一步了解我们对头脑的心理社会后遗症的理解 使用定量和定性，患者及其伴侣或配偶的颈部癌和颈部癌 方法，并开发和测试短暂夫妻干预措施的可行性 夫妻的幸福感，生活质量和关系。癌症的不确定性和生命威胁性质 诊断会导致焦虑，抑郁和创伤性压力。此外，头颈癌是 在身体和情感上具有毁灭性疾病，可能导致面部毁容，以及困难 言语，饮食和流动性。这导致生活质量差。患者的配偶也感到困扰， 照料者负担，并减少了自己的生活质量。尽管行为医学干预措施 旨在改善癌症患者的心理调整和生活质量的旨在表现出很有希望的 结果，头颈癌在这种情况下已经研究了，几乎没有研究 包括在干预中的配偶，或针对干预关系的关系。特定目标 拟议的研究是（1）表征了负面调整的负面和正面症状 随着时间的流逝，患者及其伴侣的颈部癌，并检查社会心理途径 以关系为中心的应对和关系质量可能会影响这些症状。负面症状 包括创伤性压力，抑郁和焦虑和积极症状包括增长和 生活质量； （2）定性检查头颈癌对患者，伴侣及其的影响 关系; （3）评估简短两节夫妇干预的可行性以提高质量 生活和人际关系质量。将招募八十对夫妇（n = 160）。困扰，创伤性压力，积极 结果，应对，关系质量和生活质量将在患者和合作伙伴中进行评估 癌症诊断后一个月和六个月。这些夫妇中有二十对定性 面试。将招募另外十对夫妇来测试社会心理干预的痛苦。