Brief Psychosocial Intervention for Head and Neck Cancer Patients and Partners

针对头颈癌患者及其伴侣的简短心理社会干预

• 批准号: 7226843
• 负责人: DONNA M POSLUSZNY
• 金额: $ 7.43万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-29 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7226843
• 关键词: clinical research; coping; emotions; head; head /neck neoplasm; neoplasm /cancer; quality of life; spouses

The proposed pilot research is in response to one of NCI's goals of this program announcement, which is to examine both adverse and positive effects of cancer diagnosis and treatment on patients and families, and to develop and evaluate interventions to improve quality of life and decrease negative outcomes. This prospective, longitudinal project seeks to further our understanding of the psychosocial sequelae of head and neck cancer for both patients and their partners or spouses, using both quantitative and qualitative methods, and to develop and test the feasibility of a brief couples intervention designed to improve the couples' well-being, quality of life, and relationship. The uncertainty and life threatening nature of cancer diagnoses can lead to anxiety, depression, and traumatic stress. Further, head and neck cancer is a physically and emotionally devastating disease that can cause facial disfigurement, as well as difficulties with speech, eating, and mobility. This results in poor quality of life. Spouses of patients also experience distress, caregiver burden, and decreases in their own quality of life. Although behavioral medicine interventions designed to improve psychological adjustment and quality of life in cancer patients have shown promising outcomes, head and neck cancer has been understudied in this context and there has been little research on including spouses in the intervention, or targeting the relationship for intervention. The specific aims of the proposed research are to (1) characterize both negative and positive symptoms of adjustment to head and neck cancer in patients and their partners over time, and to examine the psychosocial pathways in which relationship-focused coping and relationship quality may affect these symptoms. Negative symptoms include traumatic stress, depression, and anxiety and positive symptoms include enhanced growth and quality of life; (2) qualitatively examine the impact of head and neck cancer on patients, partners, and their relationship; and (3) to evaluate the feasibility of a brief two-session couples intervention to improve quality of life and relationship quality. Eighty couples (n=160) will be recruited. Distress, traumatic stress, positive outcomes, coping, relationship quality, and quality of life will be assessed in both patients and partners at one and six months after cancer diagnosis. Twenty of these couples will also participate in a qualitative interview. Ten additional couples will be recruited to test the feasibilty of the psychosocial intervention.

拟议的试点研究是为了响应NCI在该计划公告中的目标之一，即 检查癌症诊断和治疗对患者和家庭的不利和积极影响， 制定和评估干预措施，以提高生活质量，减少负面结果。这 前瞻性的，纵向的项目旨在进一步了解我们的心理社会后遗症的头部 和颈部癌症的患者和他们的合作伙伴或配偶，使用定量和定性 方法，并开发和测试一个简短的夫妇干预的可行性，旨在改善 夫妻的幸福、生活质量和关系。癌症的不确定性和威胁生命的性质 诊断可能导致焦虑、抑郁和创伤性压力。此外，头颈癌是一种 身体和情感上的毁灭性疾病，可导致面部毁容，以及困难， 语言、饮食和行动能力。这导致生活质量差。病人的配偶也会感到痛苦， 照顾者的负担，并降低自己的生活质量。虽然行为医学干预 旨在改善癌症患者的心理调整和生活质量的研究显示出了良好的前景 结果，头颈癌在这方面的研究不足， 让配偶参与干预，或针对性地干预夫妻关系。该委员会的具体目标 建议的研究是（1）表征调整头部的阴性和阳性症状， 随着时间的推移，患者及其伴侣的颈部癌症，并检查其中的心理社会途径， 以关系为中心的应对和关系质量可能会影响这些症状。阴性症状 包括创伤性应激反应、抑郁和焦虑，积极症状包括生长加快， 生活质量;（2）定性检查头颈癌对患者，伴侣及其家属的影响。 关系;和（3）评估一个简短的两个会话的夫妇干预，以提高质量的可行性 生活质量和关系质量。将招募80对夫妇（n=160）。痛苦，创伤压力，阳性 结果，应对，关系质量和生活质量将在患者和伴侣中进行评估， 在癌症诊断后的一个月和六个月。其中20对夫妇还将参加一个定性的 采访将招募另外10对夫妇来测试心理社会干预的可行性。