Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS
Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS
批准号:
nhmrc : GNT1099025
负责人:
A/Pr Marcel Dinger
金额:
$64.7万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
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英文摘要
Cancer is the most common cause of death from diseases in children. Neuroblastoma is the most common solid tumour in early childhood. In this application, we will establish the role of gene amplification of a novel long non-protein-coding RNA in blocking tumour suppressor gene expression and promoting neuroblastoma progression. We will also establish the anti-cancer efficacy of a novel therapy targeting the long non-protein-coding RNA.
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会议论文
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Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS
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依托单位:
lncRNAs and mesoderm formation
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依托单位:
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依托单位:
Noncoding RNAs in neural stem cell differentiation
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MicroRNA regulation of sex determination and gonad development.
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依托单位:
海外基金