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Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS

Functional characterization and therapeutic targeting of the novel long noncoding RNA MYCN-AS
新型长非编码RNA MYCN-AS的功能表征和治疗靶向
批准号:
nhmrc : 1099025
负责人:
A/Pr Marcel Dinger
金额:
$44.36万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2018-12-31

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中文摘要
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英文摘要
Cancer is the most common cause of death from diseases in children. Neuroblastoma is the most common solid tumour in early childhood. In this application, we will establish the role of gene amplification of a novel long non-protein-coding RNA in blocking tumour suppressor gene expression and promoting neuroblastoma progression. We will also establish the anti-cancer efficacy of a novel therapy targeting the long non-protein-coding RNA.
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Diagnosis of Inherited Genetic Disorders Using DNA Reference Standards
  • 批准号:
    nhmrc : GNT1139107
  • 项目类别:
    Project Grants
  • 资助金额:
    $69.08万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Marcel Dinger
  • 依托单位:
Diagnosis of Inherited Genetic Disorders Using DNA Reference Standards
  • 批准号:
    nhmrc : 1139107
  • 项目类别:
    Project Grants
  • 资助金额:
    $46.71万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Marcel Dinger
  • 依托单位:
Synthetic DNA Standards for Clinical Genome Sequencing
  • 批准号:
    nhmrc : GNT1136067
  • 项目类别:
    Development Grants
  • 资助金额:
    $87.0万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Marcel Dinger
  • 依托单位:
Synthetic DNA Standards for Clinical Genome Sequencing
  • 批准号:
    nhmrc : 1136067
  • 项目类别:
    Development Grants
  • 资助金额:
    $58.82万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Marcel Dinger
  • 依托单位:
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