Identification and characterization of a novel long intergenic noncoding RNA for the therapy of neuroblastoma
Identification and characterization of a novel long intergenic noncoding RNA for the therapy of neuroblastoma
批准号:
nhmrc : 1023001
负责人:
A/Pr Marcel Dinger
金额:
$40.1万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
Neuroblastoma is the commonest solid tumour in early childhood. Survivors suffer from lifelong disabilities due to chemotherapy. In this application, we will define the role of gene amplification of a long intergenic non-protein-coding RNA in determining the biological effects of a neuroblastoma oncogene, and promoting neuroblastoma initiation and progression. We will also define the anti-cancer efficacy of therapies targeting the long intergenic non-protein-coding RNA.
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会议论文
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依托单位:
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依托单位:
Synthetic DNA Standards for Clinical Genome Sequencing
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批准号:nhmrc : 1136067
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依托单位:
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lncRNAs and mesoderm formation
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依托单位:
Noncoding RNAs in neural stem cell differentiation
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MicroRNA regulation of sex determination and gonad development.
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依托单位:
海外基金