Appalachian Center of Translational Disparities Research

该R-24申请的具体目标是开发资源和基础设施，以进行多学科研究，将现有的关于健康促进和疾病预防的理论和知识转化为非洲裔美国人，西班牙裔和农村贫困的阿巴拉契亚人口中文化上适当的干预措施。该项目的长期目标是建立一个伙伴关系基础设施，即阿巴拉契亚人口转化研究中心（ACTRID），以便：1）制定一个有凝聚力的研究方案，解决目标人口群体中健康差距的前兆和媒介; 2）与西班牙裔、非洲裔美国人和农村弱势群体合作，解决健康差距问题; 3）向目标人群传播文化敏感的健康信息; 4）培训和指导ETSU研究人员进行社区驱动的健康差异研究。所有种族和民族的阿巴拉契亚人经历更高的发病率和死亡率比全国大部分地区，很少有人知道的双重健康差距的影响是少数民族地位和生活在一个不利的地理区域。农业与农村发展合作署将开展研究，以缩小这一知识差距。该项目将通过ETSU之间的伙伴关系实施;橡树岭联合大学，他们将为ETSU研究人员提供来自HBCU/MEIs和其他ORAU机构的导师和顾问;社区联系组织，他们将提供社区视角，以指导研究计划朝着对社区有意义的方向发展。旨在发现和干预，以改善少数民族和农村弱势群体在阿巴拉契亚的健康状况的转化研究的凝聚力计划将建立使用的前体，介质和结果的概念模型。将社区联系小组的成员纳入该方案的结构将有助于向社区成员和提供者传播研究成果，使他们能够利用这些成果改善健康;并进一步加强对非裔美国人、西班牙裔美国人和农村社区的接触。一个培训和指导计划，将建立健康差距研究的技能，并通过ORAU将ETSU教职员工与该地区和全国的研究专家联系起来，将推动ACTRID研究人员在与目标人群相关的研究计划中向前发展。

DESCRIPTION (provided by applicant): The specific aim of this R-24 application is to develop the resources and infrastructure to conduct multidisciplinary research that translates existing theories and knowledge about health promotion and disease prevention into culturally appropriate interventions among African American, Hispanic and rural disadvantaged Appalachian populations. The long-term objectives of the project are to create a partnership infrastructure, the Center for Translational Research for Appalachian Populations (ACTRID) to 1) develop a cohesive research program that addresses precursors and mediators of health disparities in targeted population groups; 2) partner with Hispanic, African American and disadvantaged rural population groups to address health disparities; 3) disseminate culturally sensitive health information to target population groups; and 4) train and mentor ETSU researchers in community-driven health disparities research. Appalachians of all race and ethnicity experience higher morbidity and mortality than most areas of the nation, and little is known about the dual health disparity effects of being of minority status and living in a disadvantaged geographic area. ACTRID will develop research to close that gap in knowledge. The project will be implemented through partnerships among ETSU; Oak Ridge Associated Universities, who will provide access to mentors and advisors from HBCUs/MEIs and other ORAU institutions for ETSU researchers; and community linkage organizations, which will offer a community perspective to guide the research program in a direction that will be meaningful to the community. A cohesive program of translational research that aims to discover and intervene to improve the health status of minorities and rural disadvantaged population groups in Appalachia will be built using a conceptual model of precursors, mediators and outcomes. Incorporation of members of community linkage groups into the structure of the ACTRID will aid in dissemination of research results to community members and providers who can use them to improve health; and further enhance entree into African American, Hispanic and rural communities. A training and mentoring program that will build skills in health disparities research and link ETSU faculty members with research experts around the region and the nation through ORAU will move ACTRID researchers forward in a program of studies relevant to the targeted population groups.