SCORE Program: New Mexico State University--Supplement

描述（由申请人提供）：这是一个补充资金的申请在新墨西哥州州立大学（NMSU）在拉斯克鲁塞斯的SCORE计划。NMSU的一个目标是扩大该机构的研究，让希望从事生物医学科学学科职业的少数民族学生参与。SCORE计划的目标是：（1）在未来四年内，将75%的SCORE子项目的研究人员转变为竞争NIH的R 01资金。(2)为了在未来四年内提高所有定期SCORE子项目研究人员的出版记录，他们正在第二个资助周期，每年在同行评审的期刊上至少增加33%的研究手稿。(3)显著提高新墨西哥州州立大学通过发展其核心研究设施进行生物医学相关研究的能力。(4)提高NMSU自我评估，评估和监测SCORE计划的能力，以实现机构自学，计划审查，支持更多计划任务和内部改进研究管理的目的。本申请包含7个研究子项目和7个试点子项目的研究建议。建议调查的具体领域包括：共生真菌的功能基因组学;癌转移; DNA中的电子传导性和光诱导电荷转移;非血红素氧化酶的铁（IV/V/VI）无机化学模型;共生细菌的发病机制;肥胖决定因素的内分泌机制;布尼亚病毒科病毒复制;婴儿及其母亲的激素、行为和认知同步性;绝经指数的相关研究;实时检测和鉴定致病细菌和病毒;产生抗氧化色素的花青素生物合成途径;感知的遗传历史和实际种族历史之间的关系作为对遗传调查态度的相关因素（ELSI研究）;以及植物盐胁迫防御的转录分析。

DESCRIPTION (provided by applicant): This is an application for supplemental funding for a SCORE Program at New Mexico State University (NMSU) at Las Cruces. A goal of NMSU is to expand research at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has as its goals: (1) To transition, within the next four years, 75% of the investigators of regular SCORE subprojects to competition for R01 funding from NIH. (2) To enhance within the next four years, the publication records of all investigators of regular SCORE subprojects, who are in their second cycle of funding, to a minimum of 33% more research manuscripts per year in peer-reviewed, refereed journals. (3) To significantly improve the capabilities of New Mexico State University to conduct biomedically relevant research through development of its core research facilities. (4) To improve the capacity of NMSU to self-evaluate, assess, and monitor the SCORE Program for the purpose of institutional self-study, program review, support of MORE Program missions, and internal improvement of research management. This application contains research proposals for 7 research subprojects and 7 pilot subprojects. Specific areas proposed for investigation include: functional genomics of symbiotic fungi; cancerous metastases; electronic conductivity and photoinduced charge transfers in DNA; inorganic chemistry models of iron (IV/V/VI) for non-heme oxidases; mechanisms of pathogenesis among symbiotic bacteria; endocrine mechanisms as determinants of obesity; Bunyaviridae virus replication; hormonal, behavioral, and cognitive synchrony in infants and their mothers; correlative studies of indices of menopause; detection and identification of pathogenic bacteria and viruses in real-time; anthocyanin biosynthetic pathways that produce anti-oxidant pigments; relationships between perceived genetic histories and actual ethnic histories as correlates of attitudes toward genetic investigations (ELSI study); and transcriptional analyses of salt-stress defenses in plants.