Phase I/II Partnership in Biomedical Discovery

生物医学发现 I/II 期合作伙伴关系

• 批准号: 7069383
• 负责人: LEWIS A JACOBSON
• 金额: $ 22.86万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7069383
• 关键词: clinical research; curriculum; experience; model; secondary schools; teacher; university

DESCRIPTION (provided by applicant): The overall objective of this phase I/II project is to develop a model of how the scientific expertise of a research university can directly impact local K-12 science education, by introducing high school teachers and students to the inquiry-based process that is scientific research. Our fundamental premises are that true science knowledge requires active engagement in scientific inquiry, and that teachers and students so engaged can become agents of change in science education. To this end, we propose to immerse selected biology teachers and high school students in an 8-week summer Research Experience, during which they participate directly in cutting-edge research in a University environment. With the participation and guidance of nine University research labs, teacher-student teams in a single lab facility will perform genetic screens for new mutations using three sets of model organisms: bacteria, yeast and C. elegans. Although these research labs have diverse objectives and employ varied experimental approaches and different techniques, there is a common thread in that they use the methods and paradigms of genetics to study health-related problems of interest and concern to the public. Weekly Curriculum Roundtable meetings among participating teachers, a Teacher Advisory Board and University faculty will focus on developing inquiry-based education modules and experiment kits, based on these model organisms, for use in high school and middle-school classrooms, and on methods and mechanisms for assessing the impact of such modules. The modules will be tested, refined and disseminated in one-week Curricular Workshops for high school teachers (who have not done the Research Experience) in project years 2-5. During succeeding years, we will provide experiment Kits for high school classes, with which teachers who have been through our programs can implement the inquiry-based curricular modules. Project evaluations aim to compare teachers who have done the 8-week Research Experience with those who have done the one-week Curricular Workshop, with respect to adoption and effective use of the inquiry-based methods and modules, to track educational and career paths of student participants, and to assess the impact on learning in high school biology.

描述（由申请人提供）： 该第一/第二阶段项目的总体目标是通过向高中教师和学生介绍基于探究的科学研究过程，开发一个模型，展示研究型大学的科学专业知识如何直接影响当地的 K-12 科学教育。我们的基本前提是，真正的科学知识需要积极参与科学探究，而教师和学生的积极参与可以成为科学教育变革的推动者。为此，我们建议让选定的生物教师和高中生沉浸在为期 8 周的夏季研究体验中，在此期间他们直接参与大学环境中的前沿研究。在九所大学研究实验室的参与和指导下，师生团队将在一个实验室设施中使用三组模型生物体（细菌、酵母和秀丽隐杆线虫）对新突变进行基因筛选。尽管这些研究实验室有不同的目标，采用不同的实验方法和不同的技术，但有一个共同点，那就是他们使用遗传学的方法和范式来研究公众感兴趣和关心的与健康相关的问题。参与教师、教师咨询委员会和大学教师之间的每周课程圆桌会议将重点开发基于这些模型生物的探究式教育模块和实验套件，供高中和初中课堂使用，以及评估此类模块影响的方法和机制。这些模块将在项目第 2-5 年为高中教师（未完成研究经验）举办的为期一周的课程研讨会中进行测试、完善和传播。在接下来的几年中，我们将为高中课程提供实验套件，通过我们的项目的教师可以使用该套件来实施基于探究的课程模块。项目评估旨在将完成为期 8 周研究经验的教师与完成为期 1 周课程研讨会的教师在采用和有效使用基于探究的方法和模块方面进行比较，跟踪学生参与者的教育和职业道路，并评估对高中生物学学习的影响。