New Sparker for Improved Electrohydraulic Lithotripsy

用于改进电液碎石术的新型火花器

• 批准号: 7052206
• 负责人: RAYMOND B SCHAEFER
• 金额: $ 9.87万
• 依托单位: PHOENIX SCIENCE AND TECHNOLOGY, INC.
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2006-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7052206
• 关键词: biomedical equipment development; computer program /software; electrodes; kidney disorder; lithotripsy; therapy adverse effect

DESCRIPTION (provided by applicant): Shock wave lithotripsy (SWL) is the treatment of choice for kidney stones. Originally the standard lithotripter generated the shock with a sparker electrode, but their use has declined because the shocks are inconsistent, cause painful side effects and the electrode must be replaced during the procedure. New types of lithotripters are more consistent and last longer, but the clinical outcomes are not as good and side effects are greater. The goal of this research is to demonstrate the feasibility of a new type of spark electrode that produces consistent shocks, can reduce side effects and last for many procedures. The long-term goal is to develop a new commercial SWL, with reduced side effects and much longer life. The work will employ an innovative methodology and design algorithm for sparker electrodes used in Navy applications. The algorithm, developed for high energy shocks, will be scaled down for SWL. Experimental measurements using electrodes developed with this new methodology will be compared to an existing lithotripter to demonstrate improvements. A successful program will lead to a new commercial system for SWL that resolves the issues with current systems, resulting in improved clinical outcomes at lower cost. Public health may also benefit from use in additional medical applications, including healing bones, treatment of tendonitis and tumor therapy.

描述（由申请人提供）：冲击波碎石术（SWL）是肾结石的首选治疗方法。最初，标准的碎石机用火花电极产生电击，但它们的使用已经下降，因为电击不一致，导致疼痛的副作用，并且在手术期间必须更换电极。新型碎石机更稳定，持续时间更长，但临床结果不太好，副作用更大。这项研究的目的是证明一种新型火花电极的可行性，这种电极可以产生一致的冲击，可以减少副作用，并持续许多程序。长期目标是开发一种新的商业SWL，副作用减少，寿命更长。这项工作将采用一种创新的方法和设计算法，用于海军应用的火花电极。该算法，开发高能量冲击，将按比例缩小SWL。实验测量使用电极开发与这种新的方法将进行比较，现有的碎石机，以证明改进。一个成功的项目将为SWL带来一个新的商业系统，解决当前系统的问题，从而以更低的成本改善临床结果。公共卫生也可能受益于其他医疗应用，包括愈合骨骼，治疗肌腱炎和肿瘤治疗。