SIV CARDIOMYOPATHY IN NON-HUMAN PRIMATES

非人类灵长类动物的 SIV 心肌病

• 批准号: 7165545
• 负责人: Richard P Shannon
• 金额: $ 6.91万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7165545
• 关键词: Primates; animal colony

DESCRIPTION (provided by applicant): This renewal application requests five years of funding for the continuation of the NENPRC's multidisciplinary biomedical research and resource program. The investigators will continue to pursue the National Institutes of Health (NIH) directed mission of utilizing the unique characteristics of nonhuman primates (NHPs) to conduct meritorious research that contributes to the understanding and solution of human health diseases. To further this objective, the emphasis of the application is to provide support for seven science cores (Behavioral Biology, Comparative Pathology, Immunology, Microbiology, Neurochemistry, Primate Resources, and Tumor Virology); to conduct pilot research; and provide Center-wide support services with emphasis on the pathogenesis of infectious diseases, treatment and prophylaxis of AIDS, basic immunology, ongenicity of herpesvirus, neurodegenerative diseases, and drug addiction. Additionally, this proposal seeks to: 1) enhance the Center's ability to serve as a regional, national, and international resource for collaborative, affiliate, and visiting scientists by providing specialized facilities, equipment, and technological expertise; 2) enhance the availability of NHPs for use in biomedical research; 3) train young investigators; and 4) provide the administrative, scientific, and primate resources infrastructure necessary to maintain and operate a Center. Four colony health-related resource projects are also included in this application as well as a five year Improvement and Modernization Program. The NENPRC, HMS, is fully accredited by the American Association for the Accreditation of Laboratory Animal Care (AAALAC) International.

描述（由申请人提供）： 该续签申请要求提供五年的资金，以继续 NENPRC 的多学科生物医学研究和资源计划。 研究人员将继续追求美国国立卫生研究院（NIH）指导的使命，利用非人类灵长类动物（NHP）的独特特征进行有价值的研究，有助于理解和解决人类健康疾病。 为了进一步实现这一目标，该应用程序的重点是为七个科学核心（行为生物学、比较病理学、免疫学、微生物学、神经化学、灵长类资源和肿瘤病毒学）提供支持；进行试点研究；提供中心范围内的支持服务，重点是传染病的发病机制、艾滋病的治疗和预防、基础免疫学、疱疹病毒的本体论、神经退行性疾病和药物成瘾。 此外，该提案旨在： 1) 通过提供专门设施、设备和技术专长，增强该中心作为合作科学家、附属科学家和访问科学家的区域、国家和国际资源的能力； 2) 提高 NHP 在生物医学研究中的可用性； 3）培养年轻研究者； 4) 提供维护和运营中心所需的行政、科学和灵长类资源基础设施。 该申请还包括四个与蜂群健康相关的资源项目以及五年改进和现代化计划。 NENPRC (HMS) 获得美国实验动物护理认证协会 (AAALAC) 国际的完全认证。