INBRE: URI: CENTRALIZED RES CORE FACILITY

描述（由申请人提供）：这个拟议的罗得岛IDEA生物医学研究卓越网络（RI-INBRE）旨在为研究能力建设提供持续的支持，无论是在博士学位授予和学士学位机构在RI，以前一直由生物医学研究基础设施网络（BRIN）奖支持。该提案有四个中心目标：1）在罗得岛州建立一个富有成效的分子毒理学合作研究计划; 2）培养有前途的本科生和研究生从事生物医学科学; 3）维护并提供包容性的最先进的生物医学核心研究设施;（4）建立有效的外展计划，招募代表性不足的科学家和学生。这些目标将由该网络的六个参与机构协作实现。将通过五个必要的核心协调网络活动。行政核心负责方案的总体指导和管理以及初级调查员的培训和辅导。生物信息学核心将协助研究人员进行数据挖掘，数据处理和分子建模需求。将通过中央数据中心提供先进的分析仪器。 核心研究设施。属于任职人数不足群体的学生和教职员工的招聘、培训和辅导将由外联核心进行。该中心的工作人员还将就网络参与者共同感兴趣的专题组织研讨会和讲习班。这四个核心将共同提高研究核心的绩效，这是RI-INBRE的主要重点活动。培训研究仪器和方法学方面的本科生和研究生骨干将是这项活动的重要成果。预计RI-INBRE，如RIBRIN，将进一步提高国家进行生物医学研究的能力，而网络调查员，谁在他们的职业生涯的早期阶段，将能够更好地为他们的个人或合作项目竞争校外研究资金。

DESCRIPTION (provided by applicant): This proposed Rhode Island IDeA Network of Biomedical Research Excellence (RI-INBRE) is designed to provide continuing support for research capacity building both at the doctoral degree granting and at the baccalaureate institutions in RI that have been previously supported by the Biomedical Research Infrastructure Network (BRIN) award. The proposal has four central aims: 1) To build a productive, collaborative research program in molecular toxicology in the state of Rhode Island; 2) To train promising undergraduate and graduate students for careers in the biomedical sciences; 3) To maintain, and provide inclusive access to a state-of-the-art biomedical core research facility; and 4) To establish an effective outreach program for recruiting underrepresented scientists and students. Implementation of these goals will be achieved collaboratively by the six participating institutions in the Network. The Network activities will be coordinated through the five required Cores. The responsibility for overall direction and management of the program, as well as training and mentoring of junior investigators, rests with the Administrative Core. The Bioinformatics Core will assist the investigators in data mining, data processing, and molecular modeling needs. Access to a sophisticated analytical instrumentation will be made available through the Centralized Research Facility Core. Recruitment, training, and mentoring of students and faculty belonging to the Under represented populations will be carried out by the Outreach Core. The staff of this Core will also organize seminars and workshops on topics of mutual interest to the Network participants. Together these four Cores will serve to improve the performance of the Research Core which is the main focused activity of the RI-INBRE. Training a cadre of undergraduate and graduate students in research instrumentation and methodology will be an important outcome of this activity. It is anticipated that the RI-INBRE, like RIBRIN, will further improve the State's capacity to do biomedical research and that the Network investigators, who are at the early stages of their careers, will be better able to compete for extramural research funds for their individual or collaborative projects.