INBRE: URI: CENTRALIZED RES CORE FACILITY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 中央研究核心基金为国际扶轮-INBRE参与者和罗德岛生物医学研究社区提供研究和培训支持，目前已进入第四个年头。核心设施的设备和资源继续向罗德岛所有学术和研究机构的研究人员提供，不收取任何使用费。在本年度，核心设施仪器和服务的使用量翻了一番。超过35个研究小组使用了该设施，平均每季度使用频率约为800次。动手用户包括6名教师、14名博士后研究员、36名研究生和25名本科生。核心设施工作人员对所有新用户进行了适当利用各种技术进行研究项目的培训。该机构的工作人员还参加了药学院提供的本科生和研究生实验室课程的教学。此外，还与仪器制造商合作举办了几次教学研讨会和培训讲习班。主题包括：用于细胞内蛋白质分析的红外成像；基本流式细胞术；以及实时定量聚合酶链式反应和逆转录聚合酶链式反应。今年收购的设备和软件包包括：用于蛋白质组学的OffGel分离系统；PD-Quest 2D Gel分析软件；带有恒温自动取样器的分析型高效液相系统；以及Milli-Q净水系统。核心设施的海报印刷服务今年已经为成员机构的调查人员免费印刷了290张海报。目前正在探索这项服务的收费结构和收费机制。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Centralized Research Core Facility is in its fourth year of providing research and training support to the RI-INBRE participants and the Rhode Island biomedical research community. The Core Facility equipment and resources continue to be made available to researchers from all Rhode Island academic and research institutions without charging any user fees. During the current year, the usage of Core Facility instrumentation and services has doubled. More than thirty five research groups used the Facility, with an average frequency of approximately 800 usages per quarter. The hands-on users included 6 faculty, 14 postdoctoral fellows, 36 graduate students, and 25 undergraduate students. All new users were trained by the Core Facility staff in properly utilizing various technologies for their research projects. The Facility staff also participated in teaching undergraduate and graduate laboratory courses offered by the College of Pharmacy. In addition, several instructional seminars and training workshops were organized in collaboration with the instrument manufacturers. The topics included the following: IR-Imaging for In-Cell Western Analysis; Basic Flow Cytometry; and Real-Time Quantitative PCR and RT-PCR. Equipment and software packages acquired this year included the following: Offgel Fractionation System for Proteomics; PD-Quest 2D Gel Analysis Software; Analytical HPLC System with Thermostatic Auto-Sampler; and Milli-Q Water Purification System. The poster printing service at the Core Facility has already printed 290 posters this year, free of charge, for investigators from the member institutions. A fee structure and a mechanism to charge for this service is being explored.