Center for Integrative Biomedical Computing

项目描述（申请者提供）：拟设立“综合生物医学计算中心”，通过其工作，解决生物电领域、基于图像的解剖学、多尺度组织建模与仿真、科学可视化等重要的生物医学研究问题。我们将利用最先进的计算技术和创新的、精心设计的软件来实现这一目标，两者结合使用，将显著推进生物医学计算研究。对于这个NCRR中心的更新，我们提出了一个令人兴奋的研究和开发目标的结合，建立在之前投资的成功基础上，并受到引人注目的新生物医学问题的推动。拟议中的NCRR中心将以以现有中心为基础并增强其优势的方式进行扩展。我们将继续开发集成的问题解决环境，为生物医学科学家提供先进的计算工具。我们还将继续在技术和生物物理方法方面进行先进的研究，以解决心脏病学和神经病学中的生物电问题。

DESCRIPTION (provided by applicant): We propose to establish the "Center for Integrative Biomedical Computing" and, through its work, to address important biomedical research problems in bioelectric fields, imaged-based anatomy, multi-scale tissue modeling and simulation, and scientific visualization. We will accomplish this by utilizing state-of-the-art computational techniques and innovative, well-engineered software, which, used in combination, will significantly advance biomedical computing research. For the renewal of this NCRR center, we propose an exciting combination of research and development aims built upon the successes of the previous investments and driven by compelling new biomedical problems. The proposed NCRR Center will expand in ways that will expand in ways that will build on and enhance the strengths of the existing center. We will continue to develop integrated problem-solving environments that make advanced computational tools available to biomedical scientists. We will also continue to pursue advanced research in technical and biophysical approaches to bioelectric field problems in cardiology and neurology. With our interdisciplinary faculty members, we will continue to educate and train researchers to engage in biomedical computing, imaging, and visualization. In response to increasing requests from the field, we have greatly extended the number of Center collaborators. We will manage these collaborations through a "life cycle", beginning with initial discussions and evaluation of potential and proceeding through fruitful scientific and technological collaborations to, in some cases, separately funded research. We have assembled a team of first-rate bioengineers and computer scientists with proven track records in performing world-class research in biomedical computing, visualization, and imaging as well as in biomedical science. This team will bring to the Center the necessary experience and expertise to continue to create robust software and deliver it to the biomedical research community. We are confident that the proposed Center will be a significant force in taking biomedical computing, imaging, and visualization to new levels of sophistication and to widespread use.