HOW CHILDHOOD FACTORS AMPLIFY RISKS OF HEAVY ALCOHOL USE

童年因素如何增加大量饮酒的风险

• 批准号: 7098293
• 负责人: JENNIFER L MAGGS
• 金额: $ 20.22万
• 依托单位: PENNSYLVANIA STATE UNIVERSITY, THE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7098293
• 关键词: British; academic achievement; adolescence (12-20); alcoholism /alcohol abuse; clinical research; disease /disorder etiology; disease /disorder proneness /risk; early experience; family structure /dynamics; human data; longitudinal human study; mathematical model; mental health; role; social status; socioeconomics; substance abuse epidemiology

DESCRIPTION (provided by applicant): The major goals of the proposed study are to study longitudinal effects of heavy alcohol use in adolescence, and to identify childhood and adolescent risk factors that amplify or minimize the impact of heavy drinking on adult status attainment, family roles, and health. Based on a life span developmental perspective on the etiology and consequences of alcohol use, this proposal seeks funds to conduct secondary data analyses on two ongoing national longitudinal studies of British individuals who have been followed from birth through midlife. Specific aims are: (1) to identify child and adolescent risk factors (e.g., social disadvantage, family relations, academic performance) that predict heavy alcohol use in adolescence and trajectories of alcohol use from adolescence through middle adulthood; (2) to examine early and middle adult consequences of heavy alcohol use during adolescence, focusing on adult status attainment in education and employment, family roles, and physical and psychological health; and (3) to identify childhood and adolescent factors that amplify or minimize (moderate) the impact of adolescent heavy drinking on status attainment, family roles, and health in adulthood. The National Child Development Study and the British Cohort Study represent unparalleled scientific resources combining major methodological strengths: nationally representative samples including a full range of socio-economic backgrounds; longitudinal designs with strong retention from birth through midlife; and multi-informant and multi-method data, including reports from parents, teachers, and participants, as well as cognitive tests, medical assessments, and national exam data. Early risk is hypothesized to increase the likelihood of experiencing alcohol-related harm in the domains of status attainment, family roles, and physical and psychological health. In particular, children with greater sociodemographic, family, and individual risk are expected to be more vulnerable to the risks of adolescent heavy drinking as they will have less human, social, and personal capital to serve as psychosocial resources during development. Primary analytic strategies will be multiple regression, longitudinal multi-level models, and causal analyses using propensity scores. The research has direct relevance for alcohol use etiology and for social policy, by identifying characteristics of individuals most likely to benefit from preventive and other assistance during the transition to adulthood.

描述（由申请人提供）：拟议研究的主要目标是研究青春期酗酒的纵向影响，并确定儿童和青少年的风险因素，这些因素会放大或最小化酗酒对成人地位、家庭角色和健康的影响。该提案基于对饮酒病因和后果的生命周期发展视角，寻求资金对两项正在进行的英国个人从出生到中年进行跟踪的全国纵向研究进行二次数据分析。具体目标是：（1）确定儿童和青少年的风险因素（例如，社会劣势、家庭关系、学业成绩），预测青春期大量饮酒以及从青春期到成年中期的饮酒轨迹； (2) 研究青春期酗酒对成年早期和中期的影响，重点关注成人在教育和就业、家庭角色以及身心健康方面的地位达到； (3) 确定童年和青少年时期的因素，这些因素会放大或最小化（缓和）青少年酗酒对成年后地位获得、家庭角色和健康的影响。国家儿童发展研究和英国队列研究代表了无与伦比的科学资源，结合了主要方法优势：具有全国代表性的样本，包括全方位的社会经济背景；纵向设计，从出生到中年都有很强的保持力；多信息、多方法的数据，包括家长、老师和参与者的报告，以及认知测试、医疗评估和国家考试数据。据推测，早期风险会增加在地位获得、家庭角色以及身心健康等领域遭受酒精相关伤害的可能性。特别是，社会人口、家庭和个人风险较大的儿童预计更容易受到青少年酗酒的风险，因为他们在发展过程中作为社会心理资源的人力、社会和个人资本较少。主要分析策略是多元回归、纵向多层次模型和使用倾向评分的因果分析。该研究通过确定在成年过渡期间最有可能从预防和其他援助中受益的个人特征，与饮酒病因学和社会政策直接相关。