Generating sophisticated multi-component scaffolding to advance neural stem/progenitor cell transplantation technology

如果干细胞移植对脑损伤的修复是有用的，必须在改善移植细胞的递送、存活和分化方面取得进展，使它们能够充分融入宿主大脑。在这里，自组装肽将被开发出来，为干细胞和神经元在细胞培养（这可能对药物发现有用）和移植到受伤的大脑后提供物理和生化支持。

If stem cell transplantation is to be useful to repair brain injury, advancement must be made to improve the delivery, survival and differentiation of transplanted cells so that they can sufficiently integrate into the host brain. Here, self-assembling peptides will be developed to provide physical and biochemical support for stem cells and neurones in cell culture (which may be useful for drug discovery) and following transplantation into the injured brain.