New Synthetic Methods to Prepare Conformationally Restricted Scaffolds

制备构象限制支架的新合成方法

• 批准号: 2885047
• 金额: --
• 依托单位: University of Nottingham
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2885047
• 关键词: New; Synthetic; Methods; Prepare; Conformationally

Small, sp3-rich, conformationally restricted scaffolds are of significant interest for potential applications such as medicinal chemistry, agrochemistry, and materials science. This project is concerned with the development of synthetic methods to access new or underexplored classes of these compounds. Strategies to be employed could involve the latest developments in catalysis, photochemistry, cycloadditions, asymmetric synthesis, and C-H functionalisation chemistry.

小的、富含sp3的、构象受限的支架对于诸如药物化学、农业化学和材料科学的潜在应用具有重大意义。该项目关注的是开发合成方法，以获得新的或未开发的此类化合物。所采用的策略可能涉及催化，光化学，环加成，不对称合成和C-H官能化化学的最新发展。