How genetic background influences the development of mesothelioma (in asbestos exposed populations)

间皮瘤是一种不可治愈的石棉诱发癌症。我们认为一个人的基因构成在很大程度上影响了他们对石棉的敏感性，这个项目的目的是找出哪些特定的基因具有这种特性。这一结果将有助于我们确定哪些石棉接触者及其家人患间皮瘤的风险最大。但也许更重要的是，这项工作将有助于为这种癌症的下一代治疗确定新的靶点。

Mesothelioma is an incurable asbestos induced cancer. We think that a person’s genetic makeup plays a large part in their sensitivity to asbestos and this project aims to figure out which specific genes have this property. The results will help us to identify which asbestos-exposed people and their families are most at risk of developing mesothelioma. But perhaps more importantly this work will help to identify new targets for the next generation of treatments for this cancer.