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Regulatory Circuits and Virulence in Candida albicans

Regulatory Circuits and Virulence in Candida albicans
白色念珠菌的调节回路和毒力
批准号:
7164436
负责人:
ALEXANDER D JOHNSON
金额:
$68.05万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-03-01 至 2011-02-28

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中文摘要
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英文摘要
DESCRIPTION (provided by applicant): The yeast Candida albicans is found as a commensal organism in the digestive tract of mammals. It is also the most common human fungal pathogen, causing both mucosal and systemic infections, particularly in immunocompromised people. This proposal covers studies of six different aspects of Candida five of which have been implicated in aspects of pathogenesis. (The sixth has not yet been studied.) These areas are (1) the reversible blastospore to filament morophologica transitions, (2) specialization of hyphal tip cells, (3) white-opaque switching, (4) mating, (5) the identification of 'virulence' genes and, (6) the possible role of regulated RNA splicing in virulence.
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Regulatory Circuits and Virulence in Candida albicans
Regulatory Circuits and Virulence in Candida albicans
Regulatory Circuits and Virulence in Candida albicans
Regulatory Circuits and Virulence in Candida albicans
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