Home Ambulatory EEG with Video Monitoring

项目描述（由申请人提供）：本项目将开发一种先进的无线家庭视频脑电图（EEG）系统，该系统基于超小型动态脑电图记录仪，结合新型同步无线高质量视频记录技术。癫痫的初步诊断通常基于癫痫发作的描述、神经学检查和常规脑电图研究。然而，癫痫发作的原因可能仍不清楚，长期脑电图监测可用于儿童和成人的确诊。动态脑电图记录仪经常用于这些长期研究，允许患者带着记录仪回家，并持续监测癫痫发作活动。目前可用的动态脑电图记录仪，记录仪的大小和不存在或有限的视频记录能力削弱了动态脑电图的好处。视频监控可以在癫痫的诊断中发挥不可或缺的作用。来自大脑的记录和视频记录使医生能够记录和分析患者的癫痫发作。视频头皮脑电图（v-EEG）是评估与神经症状相关的短暂性、阵发性临床事件患者的基础技术。动态脑电图记录仪已经存在多年，在过去的十年中，它们已经缩小了尺寸，并包括有限的视频记录。然而，即使是最先进的产品的尺寸仍然是一个障碍，特别是对于小孩来说，这使得家庭监控变得困难。动态视频监控仅限于单个系留摄像机，如果可用的话。最近，几种使能技术的广泛商业化使得创造一种微型动态脑电图记录仪成为可能，该记录仪具有同步视频，其大小约为现有系统的十分之一。所提出的先进的动态v-EEG将在梅奥诊所开发和评估一个金标准的临床v-EEG系统。

DESCRIPTION (provided by applicant): This project will develop an advanced wireless home video electroencephalograph (EEG) system based on an ultra-miniature ambulatory EEG recorder combined with new synchronized wireless high-quality video recording technology. An initial diagnosis of epilepsy is often based on the description of a seizure, a neurological examination, and routine EEG studies. However, the cause of a seizure may still be unclear and longer term EEG monitoring can be used to confirm the diagnosis in both children and adults. Ambulatory EEG recorders are often used in these long term studies allowing a patient to go home with the recorder attached and continuously monitoring seizure activity. With currently available ambulatory EEG recorders, the size of the recorder and non-existent or limited video recording capability diminishes the benefits of ambulatory EEG. Video monitoring can play an integral role in the diagnosis of epilepsy. Recordings from the brain along with video recordings allow physicians to document and analyze patients' seizures. Video scalp electroencephalography (v-EEG) is a cornerstone technology for the evaluation of patients presenting with transient, paroxysmal clinical events associated with neurological symptoms. Ambulatory EEG recorders have existed for years and in the past decade they have been reduced in size and included limited video recording. However, the size of even the most advanced products remains an obstacle, particularly for small children, making home monitoring difficult. Ambulatory video monitoring is limited to a single tethered camera, if available. The recent widespread commercialization of several enabling technologies makes possible the creation of a miniature ambulatory EEG recorder with synchronized video approximately one-tenth the size of currently available systems. The proposed advanced ambulatory v-EEG will be developed and evaluated against a gold-standard clinical v-EEG system at the Mayo clinic. PUBLIC HEALTH RELEVANCE: One of the most common neurological diseases is epilepsy. Epilepsy refers to the tendency to have unprovoked seizures, and encompasses a number of different syndromes. It has a prevalence of 0.5 to one percent. This translates to approximately two million persons in the United States. Expensive long term hospital stays for diagnostic video scalp electroencephalography (v-EEG) monitoring are typically prescribed. Ambulatory v-EEG carried out in the patient home can provide a large cost savings and patient benefit if size, ease of use, and adequate video issues can be resolved.