Home Ambulatory EEG with Video Monitoring

描述(申请人提供)：该项目将开发一个先进的无线家庭视频脑电图仪(EEG)系统，该系统基于超小型移动脑电记录仪，结合新的同步无线高质量视频记录技术。癫痫的初步诊断通常基于癫痫发作的描述、神经学检查和常规脑电检查。然而，癫痫的原因可能仍然不清楚，更长期的脑电监测可以用来确认儿童和成人的诊断。在这些长期研究中经常使用动态脑电记录器，允许患者带着记录器回家，并持续监测癫痫发作活动。对于目前可用的动态脑电记录仪，记录仪的尺寸以及不存在或有限的视频记录能力降低了动态脑电的好处。视频监护在癫痫的诊断中可以发挥不可或缺的作用。来自大脑的记录以及视频记录使医生能够记录和分析患者的癫痫发作。视频头皮脑电(v-EEG)是评估出现与神经系统症状相关的一过性、阵发性临床事件的患者的一项基石技术。移动脑电记录仪已经存在多年，在过去的十年里，它们的尺寸已经缩小，包括有限的视频记录。然而，即使是最先进的产品的大小也仍然是一个障碍，特别是对年幼的儿童来说，这使得家庭监控变得困难。动态视频监控仅限于单个系留摄像头(如果可用)。最近几种使能技术的广泛商业化使微型可移动脑电记录仪的创建成为可能，其同步视频的大小约为现有系统的十分之一。拟议的先进的动态v-EEG将在梅奥诊所根据黄金标准的临床v-EEG系统进行开发和评估。 公共卫生相关性：癫痫是最常见的神经系统疾病之一。癫痫指的是无缘无故发作的倾向，包括许多不同的综合征。它的患病率为0.5%到1%。这相当于美国大约有200万人。诊断视频头皮脑电(v-EEG)监测通常需要昂贵的长期住院治疗。如果尺寸、易用性和足够的视频问题能够得到解决，在患者家中进行的动态v-EEG可以提供大量的成本节约和患者利益。

DESCRIPTION (provided by applicant): This project will develop an advanced wireless home video electroencephalograph (EEG) system based on an ultra-miniature ambulatory EEG recorder combined with new synchronized wireless high-quality video recording technology. An initial diagnosis of epilepsy is often based on the description of a seizure, a neurological examination, and routine EEG studies. However, the cause of a seizure may still be unclear and longer term EEG monitoring can be used to confirm the diagnosis in both children and adults. Ambulatory EEG recorders are often used in these long term studies allowing a patient to go home with the recorder attached and continuously monitoring seizure activity. With currently available ambulatory EEG recorders, the size of the recorder and non-existent or limited video recording capability diminishes the benefits of ambulatory EEG. Video monitoring can play an integral role in the diagnosis of epilepsy. Recordings from the brain along with video recordings allow physicians to document and analyze patients' seizures. Video scalp electroencephalography (v-EEG) is a cornerstone technology for the evaluation of patients presenting with transient, paroxysmal clinical events associated with neurological symptoms. Ambulatory EEG recorders have existed for years and in the past decade they have been reduced in size and included limited video recording. However, the size of even the most advanced products remains an obstacle, particularly for small children, making home monitoring difficult. Ambulatory video monitoring is limited to a single tethered camera, if available. The recent widespread commercialization of several enabling technologies makes possible the creation of a miniature ambulatory EEG recorder with synchronized video approximately one-tenth the size of currently available systems. The proposed advanced ambulatory v-EEG will be developed and evaluated against a gold-standard clinical v-EEG system at the Mayo clinic. PUBLIC HEALTH RELEVANCE: One of the most common neurological diseases is epilepsy. Epilepsy refers to the tendency to have unprovoked seizures, and encompasses a number of different syndromes. It has a prevalence of 0.5 to one percent. This translates to approximately two million persons in the United States. Expensive long term hospital stays for diagnostic video scalp electroencephalography (v-EEG) monitoring are typically prescribed. Ambulatory v-EEG carried out in the patient home can provide a large cost savings and patient benefit if size, ease of use, and adequate video issues can be resolved.