Genetic epidemiology of endometrial cancer: towards understanding aetiology and improving risk prediction.

子宫内膜癌的遗传流行病学：了解病因并改进风险预测。

• 批准号: nhmrc : 1109286
• 负责人: Dr Jyotsna Batra
• 金额: $ 24.24万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/genetic-epidemiology-endometrial-risk-prediction/663078
• 关键词: Genetic; epidemiology; endometrial; cancer; towards

Studies investigating thousands of genetic markers have revolutionised our understanding of genes involved in cancer, and shown that a single gene can be associated with multiple cancers. We will conduct the largest ever study to find new genes for endometrial cancer, the most common gynaecological cancer. Our unique approach will examine >11million markers across the genome, some specifically in regions known to be important for other cancers. Findings will be used for risk prediction models.

对数以千计的遗传标记的研究彻底改变了我们对癌症相关基因的理解，并表明一个基因可能与多种癌症相关。我们将进行有史以来最大规模的研究，寻找子宫内膜癌的新基因，子宫内膜癌是最常见的妇科癌症。我们独特的方法将检查基因组中的1100万个标记，其中一些特别是在已知对其他癌症重要的区域。研究结果将用于风险预测模型。