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中文摘要
翻译
描述(申请人提供):肥胖症在美国的流行率和发病率持续上升。这些统计数据令人震惊,因为全国13个州的肥胖率超过25%。尽管大多数州的肥胖率都有所上升,但在2005年,密西西比州经年龄调整的肥胖率为总人口的31.2%。2006年,密西西比州再次成为最肥胖的州,在全国肥胖率排行榜上排名第一。人们越来越关注肥胖与慢性疾病的关系,因为肥胖是增加2型糖尿病、冠心病、高血压、血脂异常、中风和某些癌症风险的门户。这些健康问题导致了密西西比州发病率、死亡率和健康差距的主要原因。研究表明,在经历这些健康问题的人群中存在健康差距,有趣的是,服务不足的人群往往经历这些问题的比率更高。由于这些统计数据,杰克逊医疗购物中心的这项为期三年的研究建议通过在杰克逊大都会社区的成年男性和女性中进行健康促进和教育来消除与肥胖有关的健康差距。具体目标是:1)建立关于肥胖的年度健康讲习班系列,为处于这一领域研究和服务前沿的不同群体的科学家和社区领导人提供信息共享的论坛。这一系列活动将以杰克逊州立大学最近召开的关于“糖尿病和肥胖(糖尿病)”的会议为基础;2)建立关于糖尿病和肥胖(糖尿病)的年度会议;3)评估不健康生活方式行为(包括饮食和体力活动)的使用、疗效和变化,这些行为是通过使用2006年10月18日在密西西比州杰克逊市杰克逊医疗中心的NIH资源中心确定的糖尿病和肥胖相关材料获得的;4)通过焦点小组确定社区的健康需求。对重点小组进行的测试前和测试后调查以及对讲习班和资源材料有效性的评价将用于a)确定社区的需求;b)向国立卫生研究院资源中心提供宝贵的反馈;以及c)为更大的赠款资助机会提供信息。所有信息都将经过评估、翻译并在整个杰克逊大都会社区内传播。
英文摘要
DESCRIPTION (provided by applicant): The prevalence and incidence of obesity continue to increase in the United States. The statistics are alarming in that obesity exceeds 25 percent in 13 states across the country. Although the majority of states show an increase in the rate of obesity, in 2005, the age adjusted obesity prevalence rate in Mississippi was 31.2 percent of its total population. Mississippi, once again in 2006, claimed the title of the most obese, ranking number 1 in the prevalence of obesity in the nation. There is growing concern about the association of obesity and chronic diseases because obesity is a gateway to increased risk for type 2 diabetes, coronary heart disease, hypertension, dyslipidemia, stroke, and certain cancers. These health problems have contributed to the leading causes of morbidity and mortality and health disparities in Mississippi. Studies show that health disparities exist among populations experiencing these health problems, and, interestingly, the underserved populations tend to experience these at greater rates. Because of these statistics, this three-year study at the Jackson Medical Mall proposes to eliminate health disparities associated with obesity by health promotion and education in adult men and women of the Jackson Metropolitan community. The specific aims are to: 1) establish an annual health workshop series on obesity to provide a forum for information-sharing by a diverse group of scientists and community leaders at the forefront of research and service in this area. This series will build upon the recently held Jackson State University conference on "Diabetes and Obesity (Diabesity);" 2) establish an annual conference on diabetes and obesity (diabesity); 3) assess the use, efficacy, and change in unhealthy lifestyle behaviors, including eating and physical activity, obtained following the utilization of diabetes and obesity - related materials ascertained from the NIH Resource Center at the Jackson Medical Mall in Jackson, Mississippi, established October 18, 2006; and 4) identify community health needs via focus groups. Pre- and post-test surveys administered to focus groups, and evaluations on the effectiveness of the workshops and resource materials will be used to a) determine the needs of the community; b) provide valuable feedback to the NIH Resource Center; and c) provide information for larger grant funding opportunities. All information will be evaluated, translated, and disseminated throughout the Jackson Metropolitan Community.
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Administrative Core
  • 批准号:
    9003810
  • 项目类别:
  • 资助金额:
    $51.79万
  • 财政年份:
    2016
  • 负责人:
    Marinelle Payton
  • 依托单位:
Administrative Core
  • 批准号:
    8811876
  • 项目类别:
  • 资助金额:
    $44.98万
  • 财政年份:
    2015
  • 负责人:
    Marinelle Payton
  • 依托单位:
Eliminating Health Disparities Through Multi-Trans-Disciplinary Approaches
  • 批准号:
    8611741
  • 项目类别:
  • 资助金额:
    $106.48万
  • 财政年份:
    2012
  • 负责人:
    Marinelle Payton
  • 依托单位:
Administrative Core
  • 批准号:
    8352441
  • 项目类别:
  • 资助金额:
    $18.25万
  • 财政年份:
    2012
  • 负责人:
    Marinelle Payton
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: