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中文摘要
翻译
描述(由申请人提供):在美国,肥胖症的患病率和发病率持续增加。统计数据令人震惊,全国13个州的肥胖率超过25%。虽然大多数州的肥胖率都在上升,但2005年,密西西比州经年龄调整的肥胖患病率占总人口的31.2%。密西西比州在2006年再次获得了最肥胖的称号,在全国肥胖患病率中排名第一。人们越来越关注肥胖与慢性疾病的关系,因为肥胖是增加2型糖尿病、冠心病、高血压、血脂异常、中风和某些癌症风险的途径。这些健康问题是造成密西西比发病率和死亡率以及健康差距的主要原因。研究表明,在经历这些健康问题的人群中存在健康差距,有趣的是,得不到充分服务的人群往往更容易经历这些问题。由于这些统计数据,这项在杰克逊医疗中心进行的为期三年的研究提议通过对杰克逊大都会社区的成年男性和女性进行健康促进和教育来消除与肥胖相关的健康差异。具体目标是:1)设立一个关于肥胖问题的年度健康讲习班系列,为处于该领域研究和服务前沿的各种科学家和社区领导人提供一个分享信息的论坛。这一系列将建立在最近举行的杰克逊州立大学会议上“糖尿病和肥胖”(糖尿病);”2)设立糖尿病和肥胖问题年度会议(糖尿病); 3)评估使用,疗效和改变不健康的生活方式行为,包括饮食和体育活动,在利用从位于密西西比杰克逊的杰克逊医疗中心的NIH资源中心确定的糖尿病和肥胖症相关材料后获得,2006年10月18日成立; 4)通过重点小组确定社区卫生需求。对重点小组进行的测试前和测试后调查以及对研讨会和资源材料有效性的评估将用于a)确定社区的需求; B)向NIH资源中心提供有价值的反馈;以及c)为更大的赠款资助机会提供信息。所有信息将被评估,翻译,并在整个杰克逊大都会社区传播。
英文摘要
DESCRIPTION (provided by applicant): The prevalence and incidence of obesity continue to increase in the United States. The statistics are alarming in that obesity exceeds 25 percent in 13 states across the country. Although the majority of states show an increase in the rate of obesity, in 2005, the age adjusted obesity prevalence rate in Mississippi was 31.2 percent of its total population. Mississippi, once again in 2006, claimed the title of the most obese, ranking number 1 in the prevalence of obesity in the nation. There is growing concern about the association of obesity and chronic diseases because obesity is a gateway to increased risk for type 2 diabetes, coronary heart disease, hypertension, dyslipidemia, stroke, and certain cancers. These health problems have contributed to the leading causes of morbidity and mortality and health disparities in Mississippi. Studies show that health disparities exist among populations experiencing these health problems, and, interestingly, the underserved populations tend to experience these at greater rates. Because of these statistics, this three-year study at the Jackson Medical Mall proposes to eliminate health disparities associated with obesity by health promotion and education in adult men and women of the Jackson Metropolitan community. The specific aims are to: 1) establish an annual health workshop series on obesity to provide a forum for information-sharing by a diverse group of scientists and community leaders at the forefront of research and service in this area. This series will build upon the recently held Jackson State University conference on "Diabetes and Obesity (Diabesity);" 2) establish an annual conference on diabetes and obesity (diabesity); 3) assess the use, efficacy, and change in unhealthy lifestyle behaviors, including eating and physical activity, obtained following the utilization of diabetes and obesity - related materials ascertained from the NIH Resource Center at the Jackson Medical Mall in Jackson, Mississippi, established October 18, 2006; and 4) identify community health needs via focus groups. Pre- and post-test surveys administered to focus groups, and evaluations on the effectiveness of the workshops and resource materials will be used to a) determine the needs of the community; b) provide valuable feedback to the NIH Resource Center; and c) provide information for larger grant funding opportunities. All information will be evaluated, translated, and disseminated throughout the Jackson Metropolitan Community.
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Administrative Core
  • 批准号:
    9003810
  • 项目类别:
  • 资助金额:
    $51.79万
  • 财政年份:
    2016
  • 负责人:
    Marinelle Payton
  • 依托单位:
Administrative Core
  • 批准号:
    8811876
  • 项目类别:
  • 资助金额:
    $44.98万
  • 财政年份:
    2015
  • 负责人:
    Marinelle Payton
  • 依托单位:
Eliminating Health Disparities Through Multi-Trans-Disciplinary Approaches
  • 批准号:
    8611741
  • 项目类别:
  • 资助金额:
    $106.48万
  • 财政年份:
    2012
  • 负责人:
    Marinelle Payton
  • 依托单位:
Administrative Core
  • 批准号:
    8352441
  • 项目类别:
  • 资助金额:
    $18.25万
  • 财政年份:
    2012
  • 负责人:
    Marinelle Payton
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: