STATISTICAL AND DATA MANAGEMENT CENTER

本申请是作为成人艾滋病临床试验组（ACTG）的统计和数据管理中心的提案，隶属于由Robert Schooley博士领导的ACTG中央小组。我们的总体目标和宗旨是负责ACTG的所有统计和数据管理活动，包括：(1)在ACTG研究的设计和分析中提供统计领导；（二）建立和管理中央数据管理系统；(3)在科学和程序问题以及长期规划方面与ACTG调查人员合作；(4)进行数据库分析；(5)对ACTG的核心任务进行统计研究。为了确保我们的职责及时完成并产生高质量的产品，我们建立了(1)统计和数据管理中心，每个中心由管理结构、与ACTG科学委员会平行的科学部门、内部工作组和支持小组组成；(2)组建了一批高素质、经验丰富的统计科学家、程序员、数据管理人员和其他支持人员。

This application is a proposal to serve as the Statistical and Data Management Center of the Adult AIDS Clinical Trials Group (ACTG), in affiliation with the ACTG Central Group headed by Dr. Robert Schooley. Our overall objectives and aims are to be responsible for all statistical and data management activities of the ACTG, including: (1) providing statistical leadership in the design and analysis of ACTG studies; (2) establishing and administering a central data management system; (3) collaborating with ACTG investigators on scientific and procedural issues and on long-range planning; (4) conducting data base analyses, and (5) conducting statistical research on issues central to the ACTG's mission. To ensure that our responsibilities arc completed in a timely manner and yield products of high quality, we have (1) established statistical and data management centers, each consisting of a management structure, scientific sections that parallel the ACTG's scientific committees, internal working groups, and support groups; and (2) assembled a staff of highly-qualified and experienced statistical scientists, programmers, data managers and other support staff.