CORE--Analytical Chemistry

分析化学核心为中心的研究项目提供了两个重要功能。通过痕量金属成分，将分析所有环境和生物样品。在某些情况下，这将需要调整或发展方法。分析将按照书面程序进行，并遵守严格的质量控制 协议.水、聊天、土壤、室内灰尘和空气中颗粒物的环境痕量金属样品将由James Shine博士监督。Shine博士是一名生物/地球化学家，专门从事水和沉积物金属分析。 他将开发和验证方法，以确定金属在固体环境样品中的结合形式。连续提取提供了有关金属生物利用度的信息。Chitra Amarasiriwardena博士，专门从事包括植物在内的生物样品的微量金属分析。Amarasiriwardena博士已经开发了几种方法来分析血液，尿液和组织中的砷，铅和锰。 分析化学核心的第二个功能是测量和产生气溶胶。所有的研究项目都需要了解聊天的组成。分析化学核心，与工程经验的菲利普Demokritou，博士，PE和Steve Ferguson将建造暴露评估所需的采样设备。他们还将设计和建造一个系统，用于生成聊天，道路灰尘，土壤和房屋灰尘的空气传播测试样本。发生器可与颗粒浓缩器连接，用于项目3和4的动物接触研究。声学颗粒生成系统将提供一种实验室方法，用于表征与chat生成的气溶胶的传输和归宿相关的尺寸分级颗粒的金属含量。 分析化学核心由John Spongier博士领导，他也参与了项目1和2。Spengler教授在大气过程，室内空气污染和人体暴露评估方面的专业知识补充了其他分析化学核心关键人员的专业知识。

The Analytical Chemistry Core provides two important functions for the Center research projects. Through the trace metals component, all environmental and biological samples will be analyzed. In some cases this will require methods adaptation or development. Analysis will be performed in accordance with written procedures and in adherence to rigid quality control protocols. The environmental trace metal samples for water, chat, soils, house dust and airborne particulate matter will be overseen by James Shine, Ph.D. Dr. Shine is trained as a bio/geochemist and specializes in water and sediment metals analysis. He will develop and validate methods to determine the form in which metals are bound in the solid environmental samples. Sequential extraction provides information on biological availability of metals. Chitra Amarasiriwardena, Ph.D., specializes in trace metal analysis of biological samples including vegetation. Dr. Amarasiriwardena has developed several methods for arsenic, lead and manganese analysis in blood, urine and tissue. The second function of the Analytical Chemistry Core is related to measuring and generating aerosols. All research projects need to understand the composition of chat. The Analytical Chemistry Core, with the engineering experience of Philip Demokritou, Ph.D., PE, and Steve Ferguson, will build sampling equipment needed for exposure assessment. They will also design and construct a system for generating airborne test samples of chat, road dust, soil and house dust. The generator might be coupled to a particle concentrator for animal exposure studies of Projects 3 and 4. The acoustic particle-generating system will provide a laboratory method for characterizing metal content of size fractionated particle which is relevant to transport and fate of chat-generated aerosol. The Analytical Chemistry Core is led by John Spongier, Ph.D., who is also participating in Projects 1 and 2. Prof. Spengler's expertise in atmospheric processes, indoor air pollution and human exposure assessment complements the expertise of other Analytical Chemistry Core key staff.