Fetal Alcohol Spectrum Disorders: A Science-Based Prevention Curriculum

描述（由申请人提供）：拟议工作的长期目标是帮助预防一个主要的公共卫生问题，即现在被称为胎儿酒精谱系障碍（FASD）的总称。这些疾病是由于妇女在怀孕期间饮酒造成的，包括身体和精神上的先天缺陷。虽然这是完全可以预防的，但在美国，母亲酗酒是导致智力迟钝的主要原因。本申请要求为第一阶段科学高中健康和科学课程的发展提供资金，以解决酒精使用和滥用的后果，重点是FASD及其预防。该课程的开发涉及北卡罗来纳大学（UNC）和一家小型企业科学学习资源公司（SLR）之间的合作，SLR的首席执行官和该提案的其他关键人员之间现有的富有成效的工作关系促进了这一合作。北卡罗来纳大学的PI是FASD基础研究领域的专家，并具有健康和科学课程开发方面的经验。SLR在生物相关教育材料的开发和营销方面具有专业知识。拟定题为“胎儿酒精谱系障碍：迈向预防”的拟议课程，将需要将科学知识和技术从北卡罗来纳大学转移到SLR，以便纳入可销售的教育产品。这是一项及时而重要的“从研究到实践”的努力。在该项目的第一阶段，在学生和教师焦点小组，以及媒体和评估专家的协助下，我们建议开始开发关键课程材料，包括FASD信息视频，虚拟科学实验室体验和学生驱动的FASD预防活动。随着第一阶段目标的完成，我们将做好准备，成功地进行第二阶段的开发和评估，从而最终确定和分配急需的教育资源。孕妇在怀孕期间饮酒可导致一系列出生缺陷，据估计，我国每年有4万名婴儿受到影响。如果妇女在怀孕期间不喝酒，这些先天缺陷都是完全可以预防的。侧重于预防酒精引起的出生缺陷的教育资源有限。拟议中的课堂课程将针对高中学生，提供一个急需的、实际操作的、关于酒精对发育中的生物体影响的科学探索。

DESCRIPTION (provided by applicant): The long-term objective of the proposed work is to aid in preventing a major public health problem that is now referred to under the umbrella term, Fetal Alcohol Spectrum Disorders (FASD). These disorders result from a woman drinking alcohol during her pregnancy and include both physical and mental birth defects. Although it is entirely preventable, maternal alcohol abuse is the leading known cause of mental retardation in the US. This application requests funding for Phase I development of a science-based high school health and science curriculum that addresses the consequences of alcohol use and abuse, with emphasis on FASD and its prevention. The development of this curriculum involves a collaboration between the University of North Carolina (UNC) and a small business, Science Learning Resources, Inc. (SLR) that is facilitated by an existing productive working relationship between the CEO at SLR and other key personnel for this proposal. The UNC- based PI is an expert in the field of basic FASD research and has previous experience with health and science curriculum development. SLR has expertise in the development and marketing of biology-related education materials. Development of the proposed curriculum, entitled " Fetal Alcohol Spectrum Disorders: An 'I' Toward Prevention ", will entail transfer of scientific knowledge and technology from UNC to SLR for incorporation into marketable education products. This represents a timely and important "research to practice" endeavor. For Phase I of this project, with the assistance of students and teacher focus groups, as well as a media and an evaluation expert, we propose to initiate development of key curricular materials that include an FASD information video, a virtual science laboratory experience, and student-driven FASD prevention activities. With the completion of our Phase I aims, we will be well-poised to successfully conduct Phase II development and evaluation that will lead to finalizing and distributing a much-needed education resource. Maternal alcohol consumption during pregnancy can result in a spectrum of birth defects estimated to affect 40,000 babies each year in our country. Each of these birth defects is entirely preventable if a woman avoids drinking during pregnancy. Educational resources focused on prevention of alcohol-induced birth defects are limited. The proposed classroom curriculum will provide a much-needed, hands-on scientific exploration of alcohol's effects on a developing organism, targeted to high school students.