Interactive Craniofacial Normative Database (Phase II)

描述（由申请人提供）：在过去的二十年里，颅面人体测量学在临床遗传学、口腔颌面和重建整形外科中得到了越来越多的应用。定量测量使得畸形特征的诊断既客观又可靠，这对遗传学家和外科医生都是一个福音。此外，手术计划也受益于这些指标，这些指标在评估术后成功方面很有用。法卡斯的《头部和面部人体测量学》出版于1981年，在过去的20年里得到了扩展和更新，促进了这两项发展。这个颅面测量系统已经成为一个流行的标准参考，为北美提供了最广泛的规范数据库。然而，由于目前没有商业上可获得的计算机化数据库，用户目前必须依靠繁琐的硬拷贝查表，很少能接触到变量的组合函数。我们在这个STTR中的目标是通过为他们创建一个基于计算机的交互式颅面测量数据库，使这些规范的使用更加用户友好。我们的第一阶段项目成功地制作了该软件的CD-ROM版本，名为FaceValue，并得到了用户的高度评价。在阶段2中，我们将实现这个包的所有选项，并创建第二个基于web的格式。最终产品的设计目的是：(1)使用菜单驱动的、基于地标的图形用户界面，方便根据患者人口统计数据随时访问查找表；(2)允许为患者计算标准化措施，包括创建目前不可用但将由用户配置的功能；(3)从已有的数据库和颅面3D扫描仪中提供灵活的输出选项；(4)根据专业分工为人体测量协议生成报告；(5)实现数据安全和加密方法；(6)将导出的分数导出到数据库，用于文档和统计分析。

DESCRIPTION (provided by applicant): Over the last two decades, craniofacial anthropometry has found increasing application in clinical genetics and oral maxillofacial and reconstructive plastic surgery. Quantitative measurements have rendered the diagnosis of dysmorphic features both objective and reliable, a boon to geneticists and surgeons alike. In addition, surgical planning has benefited from these metrics which are useful in the assessment of postoperative success. Both of these developments have been facilitated by the publication of Farkas' Anthropometry of the Head and Face, which first appeared in 1981 and which has been expanded and updated over the last 20 years. This craniofacial surface measurement system has become a popular standard reference, providing the most extensive normative database extant for North America. Nevertheless, because there is no commercially available computerized database at the present, it is currently necessary for the user to rely on cumbersome hard-copy look-up tables with little access to combined functions of variables. Our objective within this STTR is to make the use of these norms more user-friendly by creating a computer-based interactive craniofacial measurement database for them. Our Phase 1 project successfully created a CD-ROM version of this software, entitled FaceValue, and this was highly rated by users. In Phase 2 we will implement all options for this package, and create a second, Web-based format. The final product is designed to (1) facilitate ready access to look-up tables conditioned on patient demographics, using a menu-driven, landmark-based graphic user interface; (2) permit computation of standardized measures for patients, including the creation of functions not currently available but which will be configured by the user; (3) provide flexible output options from pre-existing databases and craniofacial 3D scanners, (4) generate reports for anthropometric protocols, conditioned on professional specialization, (5) implement data security and encryption methods, and (6) export derived scores to databases for documentation and statistical analysis.