Physician Scientist Research Training in Pathogenesis of Viral Diseases

病毒性疾病发病机制的医师科学家研究培训

• 批准号: 7254124
• 负责人: Mary E. Klotman
• 金额: $ 13.42万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7254124
• 关键词: Pathogenesis; Physicians; Research Training; Scientist; Virus Diseases

DESCRIPTION (provided by applicant): Viral diseases continue to be a major threat to both the pediatric as well as the adult patient population. In recent years, the rapid emergence and spread of relatively new human pathogens such as HIV and SARS, the increasing morbidity and mortality associated with persistent and prolonged infection with agents such as Hepatitis C as well as the episodic and often unexplained reemergence of pathogens underscores the necessity of having well trained investigators that can respond rapidly to these public health demands. The goal of this research training grant is to prepare physicians (MD and MD/PhDs) to pursue careers as independent investigators specifically in the area of viral pathogenesis with a primary focus on virus/host interactions. Each of the twelve faculty members representing the key training personnel for this program has a strong track record in the area of viral pathogenesis as reflected in both publications as well as funding and a commitment to training physician-scientists. Each plays a major role in the graduate school as well as their respective departments and has developed extensive collaborative interactions which will provide the trainee a critical and accessible network of expertise. The institutional commitment in this area is reflected by the recent creation of the Emerging Infections Center that will allow continued recruitment of outstanding faculty to reflect Mt. Sinai and will provide an additional framework for trainees to benefit from the interdisciplinary nature of research in this arena. The training program is designed to extend the training period of physicians following completion of their clinical fellowships, particularly in Adult and Pediatric Infectious Diseases. The candidates will enter into their research training track in their second year of fellowship and will be candidates for funding through the training grant for two subsequent years. The major activity (representing 90% of their time) during these two years will be mentored laboratory investigation on an individual project. This experience will be complemented by participation in a weekly journal club, weekly laboratory data sessions as well as divisional, departmental, and institutional research conferences. The goal of this program is to provide the candidate with the necessary skills and training to effectively compete for mentored scientist awards as the next step in their transition to independent careers as physician scientists.

描述（由申请人提供）：病毒性疾病仍然是儿科和成人患者群体的主要威胁。近年来，艾滋病毒和非典型肺炎等相对较新的人类病原体的迅速出现和传播，与丙型肝炎等病原体的持续和长期感染相关的发病率和死亡率不断上升，以及病原体的间歇性和经常无法解释的重新出现，都强调了培养训练有素的调查人员的必要性，这些调查人员能够迅速应对这些公共卫生需求。该研究培训基金的目标是培养医生（医学博士和医学博士/博士）从事病毒发病机制领域的独立研究，主要关注病毒/宿主相互作用。代表该项目主要培训人员的12名教员中的每一位在病毒发病机制领域都有很强的记录，这反映在出版物、资金和培训医生科学家的承诺上。他们在研究生院和各自的院系中都扮演着重要的角色，并发展了广泛的合作互动，这将为受训者提供一个关键的、可访问的专业知识网络。该领域的机构承诺反映在最近创建的新发感染中心，该中心将允许继续招聘优秀的教师来反映西奈山，并将为受训者提供额外的框架，使其受益于该领域研究的跨学科性质。该培训方案旨在延长医生在完成临床研究金后的培训时间，特别是在成人和儿科传染病方面。候选人将在奖学金的第二年进入研究培训轨道，并将在随后的两年通过培训补助金获得资助。在这两年中，主要活动（占他们时间的90%）将是对单个项目的实验室调查。这种经验将通过参加每周的期刊俱乐部、每周的实验室数据会议以及部门、部门和机构的研究会议来补充。该计划的目标是为候选人提供必要的技能和培训，以有效地竞争指导科学家奖，作为他们过渡到独立职业医师科学家的下一步。