Applied Biology and Bioprocess Engineering Training

应用生物学和生物过程工程培训

• 批准号: 7257878
• 负责人: DAVID V SCHAFFER
• 金额: $ 25.9万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-09-27 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7257878
• 关键词: Biology; Engineering; Training; bioprocess

DESCRIPTION (provided by applicant): Purpose and Program Characteristics The purpose of the Applied Biology and Biotechnology training program is to provide a curriculum and research environment that prepares trainees in chemical and bioengineering, biological chemistry, cell and molecular biology at the predoctoral level for careers in biotechnology. Specifically, this program focuses on research training in areas relevant to the needs of biotechnology, pharmaceutical and chemical companies currently involved in the manufacture of products using biological routes. Trainees acquire expertise in areas such as molecular genetics, bacterial, yeast and fungal fermentation, mammalian cell culture, enzyme technology, bioproduct recovery and purification, combinatorial biocatalysis and chemistry, and biomedical applications of materials science and bioengineering. The graduate program includes laboratory and classroom instruction in cell culture techniques (mammalian and bacteria cell culture), protein and enzyme isolation, purification and immobilization, mutagenesis and gene expression, protein and nucleic acid chemistry and biochemistry, separation and purification methods, biosensors and bioinformatics. This is supplemented with seminar courses on topics spanning industrial research and development activities and advanced scientific areas, including fermentations involving recombinant organisms, tissue engineering, bioproduct recovery (including macromolecular separations), site-directed mutagenesis techniques, metabolic regulation, enzyme inhibitor design and the application of enzymes and antibodies as catalysts in organic syntheses. Lectures from internationally known scientists in a variety of related disciplines further enrich the training program. Research is conducted in the various areas described above under the supervision of the faculty mentors. Students also undertake an industrial internship during the course of their traineeship, typically at Bay Area biotechnology companies. Trainees Predoctoral students will enter the program with varying backgrounds, all holding Baccalaureate degrees in engineering or science (some with Masters degrees), and some with previous industrial experience. They will be selected on the basis of undergraduate scholastic performance, scores on GRE tests, recommendations from faculty at their undergraduate institutions and from their Berkeley mentors. Support for 12 trainees is requested. The average duration of the doctoral program in the participating departments is 5.5 years.

描述（由申请人提供）： 目的和方案特点 应用生物学和生物技术培训计划的目的是提供一个课程和研究环境，为生物技术职业生涯的博士前水平的化学和生物工程，生物化学，细胞和分子生物学的学员做好准备。具体而言，该方案侧重于与目前参与使用生物途径制造产品的生物技术、制药和化学公司的需求相关的领域的研究培训。受训人员获得分子遗传学，细菌，酵母和真菌发酵，哺乳动物细胞培养，酶技术，生物产品回收和纯化，组合生物催化和化学以及材料科学和生物工程的生物医学应用等领域的专业知识。 研究生课程包括细胞培养技术（哺乳动物和细菌细胞培养），蛋白质和酶分离，纯化和固定化，诱变和基因表达，蛋白质和核酸化学和生物化学，分离和纯化方法，生物传感器和生物信息学的实验室和课堂教学。这是补充研讨会课程的主题跨越工业研究和发展活动和先进的科学领域，包括发酵涉及重组生物体，组织工程，生物产品回收（包括大分子分离），定点诱变技术，代谢调节，酶抑制剂的设计和应用酶和抗体作为催化剂在有机合成。来自各种相关学科的国际知名科学家的讲座进一步丰富了培训计划。研究是在教师导师的监督下进行上述各个领域。学生在实习期间也会进行工业实习，通常是在湾区的生物技术公司。 学员 博士前学生将进入不同背景的程序，所有持有学士学位的工程或科学（一些硕士学位），和一些以前的工业经验。他们将根据本科学业成绩，GRE考试成绩，本科院校教师和伯克利导师的推荐来选择。需要为12名学员提供支持。参与部门的博士课程的平均持续时间为5.5年。